The series premiere takes Zane Lamprey to Phoenix, Arizona. He meets an illegal tequila moonshiner, makes a monster margarita and invents the ranch dressing beer-bomb.

Zane visits Santa Fe, New Mexico, where he meets a master margarita maker, drinks a beer that can kill chickens and eats some of the hottest chili pepper sauce in the state.

Zane rolls into Austin, Texas, where he infuses vodka with fruit, drinks the hottest bloody mary in town and tries his hand at an Austin tradition, spiking a watermelon.

Zane visits Dallas, Texas where he mixes a spicy margarita, tries some of Mama's mixes in a Double Wide and gives his competition the boot at Dallas Cowboy Stadium.

Zane drinks his way through the Big Easy. He suffers a brain freeze at Lafitte's Blacksmith Bar Shop, the oldest bar in the U.S. He tries a Hand Grenade, supposedly the strongest drink in NOLA. Finally he faces down a Hurricane at the world-famous Pat O'Brien's.

Zane hits Miami Beach, Florida, where it's time for some fun in the sun. He makes 40 mojitos in a minute at Lario's on the Beach, taps a cask of ale at premier beer bar Red Light Red Light and tries to cool off with liquid nitrogen at the Ritz-Carlton, South Beach.

Zane visits Atlanta, Georgia, where he gets a personalized beer tap, finds out what 420 is all about and meets a backwoods moonshiner. It's Drinking Made Easy, Atlanta.

Zane heads to Virginia. He downs an Orange Crush at Waterman's Surfside Grille, a Virginia Pony and a Wasabi Martini at Empire Little Bar Bistro, and a Patrick Henry at where else but Patrick Henry's Pub And Grille!

Host Zane Lamprey travels to Philadelphia, where he drinks beer from Presidential recipes, visits the oldest bar in the city, and discovers the temple shot.

Zane Lamprey visits the Big Apple. He drinks at one of the city's oldest bars, the longest bar, and a bar that's location is a secret.

Zane Lamprey visits Bean Town. He tries beer that's brewed with fruit, drinks mead, and has a beer where everybody knows your name.

Zane visits Al Capone's own Windy City. He drinks a 'French 75' at the Green Door Tavern, has a $200 Cloud Gate Martini at Tavern At The Park, and an Apricot Margarita at Chicago's most intimate bar, The Matchbox.

Zane hits up 'Beertown' He goes to 'The Bomb Shelter' where he downs Turkey Gizzard Shots, sips a 'Pink Squirrel' at Bryant's and nails some strikes in America's oldest bowling alley at Holler House. He finishes up by 'Closing Wolski's'

Zane visits the 'Gateway to the West'. He drinks at the Famous Bar on Route 66, Chuck Berry's hangout 'Blueberry Hill' and tests his vodka knowledge at Sub Zero Vodka Bar. He tops it off at St Loius' first dessert bar called Bailey's Chocolate Bar, with a Hot Chocolate Martini and a Cinnamon Stout Shake.

Zane Lamprey visits the Paris of the Plains. He tries edible cocktails, meets the creator of the Bergin Malt and squares off in a Kansas City BBQ eating challenge.

Zane Lamprey visits the Mile High City. He visits the home of Fat Tire, hits his limit at Rio Grande, and watches his buddy Steve compete in a bull ball eating contest.

Zane Lamprey visits the SLC. He visits Utah's oldest bar, dispels the myths about drinking in Utah, and learns the difference between vodka and whiskey.

Zane Lamprey visits B-Town. He has a 10-minute martini, visits a micro-distillery, and challenges Steve to a French fry eating contest in the back of a car.

Zane Lamprey heads to wine country. He makes fresh Limoncello, visits Rubicon Estates to meet with a Master Sommelier, and has a grape leaf eating contest with Steve.

Zane Lamprey visits the City by the Bay. He meets with Fritz Maytag, who lead the craft beer revolution, drinks Fernet Branca upside down, and drinks on a mobile island.

Zane Lamprey visits Sin City. He drinks a bacon martini, eats deep-fried Oreos at Aces & Ales, and hits the tables in Planet Hollywood.

Zane Lamprey visits San Diego. He drinks at Noble Experiment, a hidden speakeasy, drinks schooners or beer at the Shore Club, and hangs out with an Arrogant Bastard.

In the final episode of season one, Zane returns home to Los Angeles. He drinks out of fruit at Paradise Cove, takes a flight at Blue Palms Brew House and stops by Musso & Franks, a Hollywood institution.