Ethan Hunt and team continue their search for the terrifying AI known as the Entity — which has infiltrated intelligence networks all over the globe — with the world's governments and a mysterious ghost from Hunt's past on their trail. Joined by new allies and armed with the means to shut the Entity down for good, Hunt is in a race against time to prevent the world as we know it from changing forever.

When an old acquaintance is murdered, Wolff is compelled to solve the case. Realizing more extreme measures are necessary, Wolff recruits his estranged and highly lethal brother, Brax, to help. In partnership with Marybeth Medina, they uncover a deadly conspiracy, becoming targets of a ruthless network of killers who will stop at nothing to keep their secrets buried.