Season 0 of 1000-lb Sisters premiered on December 20, 2020.

Season 1 of 1000-lb Sisters premiered on January 1, 2020.

Tipping the scales at over 1,000 pounds combined, the Slaton sisters try to lose enough weight to qualify for and undergo life-changing bariatric surgery and pursue their dreams.

Season 2 of 1000-lb Sisters premiered on January 4, 2021.

Tipping the scales at over 1,000 pounds combined, the Slaton sisters try to lose enough weight to qualify for and undergo life-changing bariatric surgery and pursue their dreams.

Season 3 of 1000-lb Sisters premiered on November 15, 2021.

Tipping the scales at over 1,000 pounds combined, the Slaton sisters try to lose enough weight to qualify for and undergo life-changing bariatric surgery and pursue their dreams.

Season 4 of 1000-lb Sisters premiered on January 17, 2023.

Season 5 of 1000-lb Sisters premiered on December 12, 2023.

The Slaton sisters are back and it’s the heaviest season yet.

Season 6 of 1000-lb Sisters premiered on October 8, 2024.

Season 7 of 1000-lb Sisters premiered on April 15, 2025.