Sesong 1 av My Next Guest Needs No Introduction with David Letterman hadde premiere 12 Januar 2018.

Former President Barack Obama reflects on political tensions and his family's life after the White House, and Dave visits Selma with Rep. John Lewis.

Sesong 2 av My Next Guest Needs No Introduction with David Letterman hadde premiere 31 Mai 2019.

Dave welcomes Kanye West, Ellen DeGeneres, Tiffany Haddish, Lewis Hamilton and Melinda Gates for a fresh crop of funny and insightful interviews.

Sesong 3 av My Next Guest Needs No Introduction with David Letterman hadde premiere 20 Oktober 2020.

Dave returns with a set of intimate, in-depth interviews featuring megastars Dave Chappelle, Kim Kardashian West, Lizzo and Robert Downey Jr.

Sesong 4 av My Next Guest Needs No Introduction with David Letterman hadde premiere 19 Mai 2022.

Dave gets back out in the world and digs deep with guests Billie Eilish, Kevin Durant, Ryan Reynolds, Julia Louis-Dreyfus, Will Smith and Cardi B.

Sesong 5 av My Next Guest Needs No Introduction with David Letterman hadde premiere 11 Juni 2024.