Season 0 of Honey and Clover premiered on December 23, 2005.

Season 1 of Honey and Clover premiered on April 15, 2005.

Yuuta Takemoto, a sophomore at an arts college, shares a cheap apartment with two seniors—the eccentric Shinobu Morita, who keeps failing to graduate due to his absenteeism, and the sensible Takumi Mayama, who acts as a proper senior to Takemoto, often looking out for him.

Takemoto had not given much thought to his future until one fine spring day, when he meets the endearing Hagumi Hanamoto and falls in love at first sight. Incredibly gifted in the arts, Hagumi enrolls in Takemoto's university and soon befriends the popular pottery student Ayumi Yamada. Ayumi is already well acquainted with the three flatmates and secretly harbors deep feelings for one of them.

Hachimitsu to Clover is a heartwarming tale of youth, love, soul-searching, and self-discovery, intricately woven through the complex relationships between five dear friends.

Season 2 of Honey and Clover premiered on June 30, 2006.

Back from his journey across Japan, Yuuta Takemoto reminisces about his college life so far. He has matured significantly since his second year and is motivated to move forward.

Feeling more confident than ever before, he finally confesses to Hagumi Hanamoto, the girl he has been in love with since their first encounter. However, Hagumi has been confused by her attempts to understand the mysterious Shinobu Morita. Hiding behind a playful demeanor, Morita may be the most burdened by his own potential. Meanwhile, Takumi Mayama has become a full-fledged working adult and has landed Ayumi Yamada several pottery orders through his company in an act of friendship.

The five youths continue to face individual hardships in academics, work, love, and friendship as they push each other toward the paths that they are destined to walk.