The Lang and O'Leary Exchange is a Canada business news television series, which airs weekdays on CBC Television and CBC News Network. Hosted by CBC's senior business correspondent Amanda Lang and entrepreneur/investor Kevin O'Leary, the series presents a summary of the day's major business stories in a manner similar to Lang and O'Leary's earlier Business News Network series SqueezePlay.

In the opening segment, "The Big 5", Lang introduces the top business stories of the day and O'Leary provides commentary, with Lang often acting as devil's advocate in regards to O'Leary's free-market philosophy. A later segment, "My Money", follows a similar format in regards to discussions of various investment opportunities and strategies. The remaining segments consist of various interviews and roundtables with businesspeople, economists, journalists and other newsmakers, handled by either Lang alone or both Lang and O'Leary.

The show originally aired as a half-hour daily series, starting at 4:30 p.m. Eastern. As of March 1, 2010 The Lang and O'Leary Exchange became an hour-long show starting at 7 p.m., pre-taped earlier in the evening, and aired on the CBC News Network. In September 2012, the show was revised into two half-hour formats, and gained an airing at 6:30 p.m. local time for the first half hour on CBC Television following local newscasts. They now feature the Big Three in the first half hour, and the top two in their second half hour.