La temporada 1 de Monty Python's Personal Best se estrenó el 22 de febrero de 2006.

Each episode includes members of the original Monty Python troupe performing in favorite clips from their unorthodox television series repurposed with exclusive new material. Each of the five living Pythons — John Cleese, Terry Gilliam, Eric Idle, Terry Jones and Michael Palin — produced and wrote his own episode, and collaborated to create the sixth special in honor of deceased member Graham Chapman.