In 1989, Richard Mallory is found shot dead in the brush off the side of a Florida highway, just the first of seven murdered men found in a similar setting. Their predator is Aileen Wuornos, a woman fleeing a troubled past and yearning for a connection. Instead of finding of love, The Damsel of Death develops a simmering rage in her heart, that finally explodes when she picks up her first victim.

Before he hunted down his first victim in the wilds of Alaska, Robert Hansen was a successful businessman with a family in Anchorage, but his intense feelings would build into a dark desire to exert the ultimate control over 17 victims.

Known primarily for the murders of University of Florida students, a man's first murders were in his hometown of Shreveport, La.; the man dreamed of having a loving family as an adult, but his dark fantasies drove him to destroy a family instead.

African American women in the Mt. Pleasant neighborhood of Cleveland were vanishing; Anthony Sowell found the control he was so desperate for when he overpowered his first vulnerable victim -- a woman only hoping to connect with a friendly face.

The articulate and boastful killer is remembered for terrifying the coastal town of Santa Cruz, where he picked up and dismembered hitchhiking college students in the early 1970s.

In rural Epping, N.H., everyone knows Sheila LaBarre as an eccentric widow who loves her rabbits; her turbulent childhood in Alabama, a coma-induced vision, and the death of her wealthy husband all send Sheila on a warped mission to kill.

Someone is killing young African American women in Charlotte, North Carolina and the police seem unable to stop it. What the police don't realise is that the cases all have a commonality: a connection with Henry Louis Wallace.

The Genesee River Killer

Serial killer Arthur Shawcross tells a lot of stories about his life before he began to kill. Abuse, bestiality, cannibalism...but is any of it true? And if not, what shaped his trajectory from "Artie Oddball" to murderer? He might have been known for killing women along Rochester's Genesee River, but his first murder was years earlier and the culmination of years of dark fantasies.

The Bayou Strangler

Growing up gay and effeminate in the hyper-masculine Bayou was tough on Ronald Dominique. But that's not why Ronald began to kill African American men. An inability to connect and a jail sexual assault would cement his decision to ultimately kill his first victim, tragically the beginning of years of senseless murder.