Investigating the death of his cleaning lady's nephew, Coliandro uncovers an extreme fighting ring involving a series of wrestlers who are systematically drugged to relieve pain and fatigue. Helping him unravel the case is Veena, a beautiful and athletic fighter who escaped from this group of modern-day gladiators.

Coliandro believes Gamberini has relapsed into his old gambling habit and, trying to help his friend, infiltrates an underground gambling ring. However, in doing so, he undermines an ongoing investigation initiated by Longhi and puts Giacomino, whom he has hired as a consultant, Gamberini, and himself in grave danger. Thanks to the help of Ambra, the girlfriend of one of the gangsters, the inspector manages to escape.

Coliandro answers the mysterious phone call from a sensual female voice, telling him that a bomb is ready to explode unless he—and he alone—runs to defuse it. But there's more than one bomb ready to explode.

Coliandro is contacted by a girl who needs help: her boyfriend disappeared after stealing a smartphone and finding footage of a gang of Russian criminals inside. The young woman turns to the inspector because she often hears him mentioned by her aunt, the deputy prosecutor Longhi, who however believes that Coliandro is not a good policeman.

Coliandro witnesses an illegal motorcycle race between two riders, but one of them loses control and causes the other to crash, killing him. The inspector and Buffarini manage to save the motorcyclist responsible for the accident and find refuge in the Carabinieri station, but they must contend with the bloodthirsty local boss, the deceased rider's brother, who seeks revenge.