The MyNetworkTV telenovelas were Fox Television's attempt to create a successful low-cost programming franchise by adapting Spanish-language telenovelas for U.S. viewers. While originally planned for syndication, the format became the original lineup of MyNetworkTV in 2006. Six limited-run serials were produced, each running about 65 episodes, and at least three others were halted in development.

New episodes aired from Monday to Friday – and weekend clip shows recapped the shows' storylines. Producers planned continuous cycles of thirteen-week serials with no repeats. Once one series ended, another unrelated melodrama would begin the following week. In total, MyNetworkTV planned to air 600 hours of original dramatic programming in HDTV every year.

The telenovela format was unsuccessful and ratings were unexpectedly low. An average of about 781,000 people tuned in to watch the telenovelas, according to Nielsen Media Research. Parent company News Corp. said MyNetworkTV lost two million dollars per week with the all-telenovela lineup.

Under new network president Greg Meidel, production and development stopped in early 2007. "Trying to get people to watch serialized dramas every night on MyNetworkTV was asking the impossible," he remarked. The novelas premiered on September 5, 2006 and last aired on July 18, 2007.