Firefighters made a desperate effort to save the Huggins family of seven, 2 adults and 5 children, from a blazing fire in Akron, OH, but rescuers were too late. Police declared the fire was no accident and began an arson investigation, which included another unexplained fire a year earlier on the same block that killed a beloved elderly couple, Gloria Hart and Lindell Lewis.

A camper gathering firewood in Arizona's scenic Sunset Crater National Park was shocked to discover the body of 27-year-old Sasha Krause in a traditional long dress, wearing black shoes. Her Mennonite family and friends in New Mexico were stunned--she had no known enemies and was a beloved, studious young woman, who loved books. How did she end up dead so far from home? [also shown as S3:E3]

Mengqi Ji, a Chinese exchange student, found a career and a love match with Joe Elledge in the idyllic Missouri university town of Columbia; they married and started a family. It was a shock to her loved ones when she disappeared in October 2019 apparently to be with another man, leaving both her child Anna and her cell phone behind. Her remains were eventually found by a hiker in February 2020. [also shown as S3:E2]

When Joleen Cummings, a hairstylist at Tangles Hair Salon in Yulee, FL, failed to pick up her children for a planned celebration, and was reported missing by her ex-husband. Investigators discovered a bloody scene at the salon, but the hairstylist and her SUV were gone. [also shown as S3:E5]

Ten days after Memphis NBA player Lorenzen Wright went missing in 2010, the player's body was found in a swamp, shot 11 times. He called 911 but never spoke; gunshots are heard in the background. Police search for clues to identify the killer but the case stalled for 3 years until an inmate confessed but was found unproven; it stalled again for 4 more years until a deeper investigation uncovering a murder plot. [also shown as S3:E4]

Makeva Jenkins, a successful businesswoman and pregnant mother of three, boasted on Facebook that she had grown her business to six figures from being homeless. But just hours later, she was shot dead with a bullet to the head. Her husband Euri Jenkins, her brother Quay, and Euri's friend Dametri all relayed to police that a masked intruder had shot and killed her. Police soon uncover a murder-for-hire plot.

In March 1993, two newspaper carriers driving down a rural road spotted what they thought was a doll but which turned out to be, in fact, a newborn baby's body. The coroner determined that the baby boy had been born alive; but his origin was a mystery. Despite dozens of leads and even a hidden camera placed at the cemetery in hopes that the child's mother would show up, no arrests were made for 25 years. Then, with modern DNA and familial genealogy techniques, the cold case was solved.

Todd Kendhammer called 911 in a panic, describing a freak accident that occurred while he was driving with his wife, Barbara, in the passenger seat. He said a metal pipe had fallen from a passing flatbed truck, piercing the windshield and fatally injuring his wife. But Wisconsin police were suspicious of Todd's responses in the interrogation room, when his story continued to change, and his alibi didn't check out. Forensic details from the autopsy report cast further doubt on his story.

In Florida 2015, 36-year-old mother of two Amanda Colley was starting her life over after a contentious divorce and an ongoing custody battle with her ex-husband, James. One summer night, she returned to a ransacked house; her boyfriend Lamar and two of her girlfriends, Lindy and Rachel, arrived to join her as police were called. Then, gunshots rang out, glass shattered, and after 911 was called from inside the house, more shots were fired; Amanda and Lindy, a mother of three, were both dead, and Rachel was injured. (Lamar had run before the shooting as he knew he was the target.) The gunman took off before police arrived.

Jazz trumpet player Scott Sessions, from Greeley, CO, fails to show up for a gig. A few days later, his body is found wrapped in plastic and duct tape, partially burned, and hidden in a forest in Pingree Park, CO. Detectives soon discover a relationship that Scott didn't tell his loved ones about.

When Ohio State senior Reagan Tokes fails to respond to messages from her parents, they fear the worst. Their nightmare becomes a reality when a 911 caller reports the discovery of a female body in the local park, shot execution style. Knowing a brutal killer is on the loose, detectives race to solve the crime and soon discover CCTV footage.