Onodera Mariya’s married life was supposed to have been happy but turns out shortlived when her husband Tatsuya suddenly disappears without a trace. At her wit's end, she heads for a heart-shaped island in Okinawa that Tatsuya had once spoken of. On the other hand, at a time earlier than this, Tsuruta Kameko, who has been working as a midwife in Tokyo, gets disgusted with the mentality of frivolous girls who regard abortion as reasonable, and a compromise in natural childbirth because of the hospital, wins a large sum of money in a lottery and leaves for a trip around the world. However, she learns that the Okinawan archipelago that she first stopped at is suffering from a shortage of midwives and decides to set up the ideal maternity hospital down there. These two women of different generations meet in the southern islands. The islanders including Kameko warmly embrace Mariya just like the Okinawan words say, “If we meet by chance, we’re all brothers and sisters”…

繁华大都市，安西玛丽亚（仲里依纱饰）和小野寺达也（沟端淳平饰）组成家庭，但是无子的婚后生活被巨大的落寞隔阂之感笼罩。不久达也失踪，失落的玛丽亚为寻找丈夫，启程前往达也曾提到过的心形小岛——美波间。人到中年的鹤田龟子（余贵美子饰）是一名助产士，她对于自然的分娩方式在医院被扭曲的现象感到厌烦。这时，一名无力支付引产手术费的俱乐部女郎用彩票抵债，却让她中了大奖。龟子辞职后开始自由自在的环球旅行，旅行的第一站就是美波间岛。本打算享受后半生的龟子却在长老长井朗（伊东四朗饰）的极力劝说下留在当地开起了助产医院。年龄不同的两个女人，在美波间岛相遇了。曾经做过美容师的玛丽亚依托龟子的医院开起了沙龙。两个女人的全新人生，在冲绳的美丽小岛上开启

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