Growing up between McAllen, Texas and Río Bravo, Tamaulipas. Ana Brenda Contreras moved to Mexico City at the age of 15, to participate in the reality show Pop Stars, where she was a finalist and member of the band, t'detila. They recorded an album with the same name. In 2003, she joined the Center for Arts Education Televisa to study acting. In 2005, she appeared as Juanita in the telenovela Barrera de amor, produced by Ernesto Alonso.

Ana Brenda Contreras é uma atriz e modelo norte-americana. É conhecida por seus papéis como Maricruz e Maria Alessandra Mendonça em Coração Indomável, Maura Albarrán em Sortilegio e Aurora Alcázar em Teresa. Em 2018, interpreta Crystal Jennings na série televisiva Dynasty.