Maria Isabel Pagunsan Lopez-Melrod is a Filipino actress and beauty pageant titleholder. Lopez won the Binibining Pilipinas Universe 1982 and represented the Philippines in the 31st Miss Universe Pageant in Lima, Peru.

She became known as the first beauty queen and actress appearing in Sex in film. Lopez was married to Hiroshi Yokohama, and then later married Jonathan Melrod in the United States. She is a mosaic artist and has appeared in various roles in Philippine cinema and television.