Emma and Anaïs are best friends and yet everything in their life seems to set them apart, their social backgrounds but also their personalities. From the age of thirteen to eighteen, Adolescentes follows the two teenagers during these years where radical transformations and first times punctuate daily life. Through their personal stories, the film offers a rare portrait of France and its recent history.

After a chance encounter on the DC metro, Ryan and Julisa spend the next twenty-four hours discussing their hopes, dreams, and fears. Slowly but surely, they reveal more and more about themselves, and fall in love.

An unexpected guest, severed family ties, friendships on the verge of ending. Before they completely drift apart; Ali, Büşra, Efe, and Güray find themselves in a spiral of loneliness at the collapse point of their personal lives.