Moederhart tells the story of three sisters and their brother - Zeynep, Emre, Cemre and Aysun - who, together with their mother, Nefise, are left in poverty after the sudden death of their father. As a single mother, Nefise often feels powerless, but with the help of a family member, she starts working for a rich family in a mansion. The house is owned by Muzaffer and his brother, Onur, who also run a company together.