The Carretera de la Muerte - the road to death. Year after year many people die here. Omar and his co-driver Jaime drive across the Andes, encountering cyclists, mountain bikers, and coca-farmers on the way.

The Sichuan Tibet Highway leads through fascinating landscapes and remote areas up to the Himalayan Mountains. Truck driver Ren Taiping makes his trip to the Tibetan capital city of Lhasa.

The Halsema Highway, on the island of Luzon, leads right through the Philippine jungle with its frequent fog and heavy rainfalls making it highly dangerous. A bus driver and a taxi driver make the challenging trip.

The Canadian ice roads last for only a few months in the winter, the only time of the year when goods can be transported by road up to Northern Manitoba. Truckers Vlad, Hugh, and Scott make their long journey to a village.