Dr. Jeff performs a surgery he's never done before on a dog with labored breathing. A senior canine was abandoned by his owner and the staff must find him a new forever home, while neglected ornate box turtles are saved by Dr. Baier.

A daredevil dog is saved by Dr. Jeff after it jumped from a fast-moving car on the highway. Dr. Don solves a medical mystery, while a couple's mischievous rescue guinea pigs cause a stir.

Dr. Jeff performs surgeries with the help of two vet students. A tribe of fainting goats is seen by Dr. Jeff and Hector, while Dr. Amy discovers why a cute and cuddly kitten is teary-eyed.

Dr. Jeff and his team lend a hand at Lakota Reservation in South Dakota. Back at the clinic, Amy debates emergency surgery for a French bulldog who ate his favorite toy, while Susan finds the perfect forever home for a lovable canine called Koda.

Dr. Jeff reveals the cause behind a beloved senior dog's mysterious lump. A cat called Tigger is monitored for unusual eating habits. An owner learns the perils of purchasing her pup online after it becomes sickly, and Petra shows off her guinea pigs.

Dr. Jeff and Petra train new vets at a wildlife sanctuary in Mexico. While there, they spay an endangered jaguar, and help an injured osprey. At the clinic, a Great Dane comes in with wounds after battling an air conditioner.

Dr. Jeff discovers a large mass on a loveable canine. Dr. Don helps Kelly the vet tech with her dog's sun-damaged nose, while Dr. Baier and Hector join forces to treat wild bison.

Coco the Frenchie needs Dr. Jeff's help to remove a large lump from her face. Vet tech Christine faces her fear of birds while helping pigeons from Rocky Mountain Adventures, and Dr. Jeff and Baier aid a red-back turtle with an infected foot.

Dr. Jeff comes to the rescue of a pup that's fallen from a trampoline.

Dr. Jeff and vet tech Ben head to a remote island in Panama to help with the pet population. A feisty terrier loses the battle against a German shepherd pup, while a sickly Sphynx kitten has been relinquished and needs serious medical attention.

A litter of kittens is rescued; a dog is struck by a car.

A dog called Mac is rushed in after being hit by a car. Dr. Amy performs surgery on a canine called Rebel who was impaled with a stick, while Dr. Baier helps Kino, a hound in heat even though she's been spayed twice.