Lives hang in the balance as the members of Station 19 continue to fight a raging inferno inside a skyscraper. Meanwhile, Pruitt’s health is in grave danger at Grey Sloan; and a seasoned firefighter with a mysterious past arrives at Station 19, leaving everyone to wonder what the future holds.

It’s a life-and-death situation when a young boy falls into water pipes beneath the city of Seattle. With the clock ticking, the firefighters of Station 19 jump into action to save his life.

When Station 19 receives a call from concerned neighbors regarding a resident in their apartment building, the team heads out to investigate. When they arrive to evaluate the scene, they're shocked by what they find inside. Meanwhile, in an effort to create a solid working relationship between the fire and police departments, Ryan takes an unlikely member of the team on a ride-along.

Everyone is less than enthusiastic when Sullivan assigns each member of the crew a specialty skill to learn. During a house call, Ryan is caught off guard when he comes face-to-face with someone from his past; and Sullivan, Andy and Maya handle a structure fire in a derelict building.

Captain Sullivan continues his efforts to bring together the fire and police departments by hosting a training seminar that does not go as planned. Meanwhile, Ben and Miranda have an honest conversation about their marriage, leading Miranda to make a tough decision about their future.

Just when Ryan agrees to talk it out with his dad, Greg Tanner makes an unexpected visit to Station 19, leaving Ryan and others confused. In an effort to connect with his crew, Captain Sullivan enlists the help of an unlikely source for some bonding tips.

As the team gathers for a Friendsgiving celebration at Dean’s, a violent windstorm touches down in Seattle. As the storm picks up speed, creating dangerous fire conditions, the crew must put the festivities on hold and report for duty, leaving some of them in a life-threatening situation.

In the aftermath of the windstorm, Andy and Sullivan’s fates remain unknown while trapped in the overturned aid car. Meanwhile, back at the station, the team confronts Jack about his well-being; and when it’s safe enough to venture out, they search for their fellow firefighters in a race against time.

When Andy, Maya and Dean respond to a call, they find an injured woman with amnesia; but soon into the treatment process, they realize there is much more to her story. Meanwhile, Captain Sullivan takes Ben and Jack on a house call that quickly becomes a close call for the patient they’re treating, while Ryan may not have seen the last of his father, Greg.

Jack and Maya are called to treat people stuck in a subway train and discover a potential threat to the passengers and themselves. Meanwhile, Travis, Ben and Dean get pressured into inviting Sullivan to help repaint walls in Travis’ house and come to a surprising conclusion about Sullivan.

When an RV crashes into Station 19, the team races against the clock to save lives and secure the building’s compromised structure. Meanwhile, a surprise delivery arrives at reception.

While struggling to help victims of a crash on a desolate road, Vic finds the courage to confront a difficult situation. Meanwhile, Ben prepares to go out for Medic One, causing some concern over his current Station 19 responsibilities, and Pruitt spends time with a special someone.

A blackout in Seattle creates dangerous situations throughout the city and the members of Station 19 head out on calls, including locating a missing girl and helping a man on life support where every second counts.

When Station 19 gets called to a structure fire at a coffee processing plant, the team risks their lives to save Station 42’s captain. Meanwhile, Ripley and Vic consider a shocking option to save their relationship; Andy gets some surprising news about some of her fellow crew members, and Pruitt takes on a new position.

Following a life-threatening situation that left the future of a member of Station 19 unclear, the crew gathers to face the outcome. Andy and Ben respond to a man impaled by a chandelier. Meanwhile, Station 19 is called upon to organize shipments of supplies and assist with wildfires in Los Angeles.

The members of Station 19 pack their gear and head to Los Angeles, California, to help battle a deadly wildfire raging out of control. While the team works to evacuate residents, they meet Terry, and Ben makes a split-second decision that changes both of their lives.