A new season brings new challenges as Villalobos Rescue Center expands beyond New Orleans and into the surrounding swamps, opening a satellite shelter in nearby Assumption Parish.

Stray dog from the swamp comes to Villalobos; an overwhelmed owner hands over two sickly puppies to Tia; and a Villalobos favorite may have found a home.

A parolee takes the lead in a rescue in an attempt to assume more responsibility; a woman looks for a dog that will be comfortable around her chickens; Tia saves a pit bull with scars that indicate a painful history.

Matt hurries to save puppies that are under railroad ties; a California couple search for a new best friend; bad news arrives about one of Villalobos' favorite dogs.

A family from New Hampshire visits Villalobos in hopes of finding a new companion; an alert about an aggressive dog results in a heartbreaking discovery; Earl visits a spine specialist to address his chronic pain.

A mission to rescue a stray turns into a terrifying ordeal for Matt, forcing Tania to take the lead. Meanwhile, a new recruit experiences the heartbreak associated with a life in dog rescue; and one of the center's favorites has a shot at a forever home.

A dog is tied up in an abandoned house, presenting a unique challenge for Tia to rescue it. Meanwhile, Tania works hard to find a home for one of Villalobos' residents, but the adoption could fall through due to a health scare.

After a dog is shot, Tia races to save his life. Then, Matt and Lizzy scramble to rescue a scared and sick puppy running loose on the busy roads near the warehouse. And after red-flags are raised during a home check, Tia faces an agonizing decision.

Tia and her staff scramble to coax a scared dog, hiding under a vehicle, to safety. Tania's in-laws are seeking a new addition to their home. And, Tia's sone Moe and his fiancée Lizzy prepare for their wedding day.

A pit bull is abandoned by its owners in an empty house; a mother and daughter come from Oklahoma looking for a new best friend; Tia's dog Jethro becomes ill.

A dog has a tumor that could affect its chances of getting a forever home; an aggressive dog becomes a danger to the staff; Villalobos hopes to bring a stray and its owner together again.

With the holidays quickly approaching, Tia surprises her family, the parolees and every dog at the rescue with an extraordinary gift. But turning this giant gift into something Villalobos can actually use will require herculean effort.

In one of the worst cases of neglect Tia has ever seen, the team tries to nurse a severely malnourished dog back to health. And, ten years after Hurricane Katrina, one of the survivors finally has a chance at a forever home.

When a tornado tears through New Orleans, Tania takes charge - but is furious when the parolees fail to show up to help. And a fellow pit bull trainer seeks Tia's help adopting a dog she can put to work.

Tia enlists Matt's help adopting a patrol dog out to his former home, Dixon prison. Then, Tia gets a call about two dogs left behind when their owners abandoned the property. And, Tania has trouble letting go when Brandi is up for adoption.

When a reputed dognapper dumps a dog at Villalobos, Mariah scrambles to find the owner. A new parolee needs Tia's help when he realizes he is in over his head. And, after having her last adoption fall through, Smack has a second chance at a loving home.

An outbreak of disease in the swamps threatens the dogs. Tania goes out on her own to save a stray pit from the streets and is faced with a difficult rescue. And after years of waiting for a forever home, Jackson finally gets his shot.

Tia is short-staffed, but finding a parolee who is prepared for the demands of the job is proving difficult. Then, when Tia hears about a pack of pit bulls running in the street, the team races to the rescue and find an overwhelmed owner.

When a sinkhole threatens to swallow a nearby neighborhood, Tia teams up with cat expert Jackson Galaxy to rescue dozens of cats. And, after finding a neglected mama dog near the warehouse, Tia and her team span out to try and find her puppies.

After seeing their dog rescued on an episode of the series, a family contacts Tia in the hope of being reunited. Tia is forced to confront Earl about his sudden change in behavior. And, Matt makes a life-altering decision.