Kim Jun-wan waits for a response from Lee Ik-sun, who says she needs some time. Jeong-won breaks painful news to the family of his longtime patient.

An unforeseen problem just before a surgery forces Jeong-won to make a tough decision. Meanwhile, Jun-wan is put on edge in the operating room.

Distracted by a problem in his personal life, Do Jae-hak struggles to get through the day. Meanwhile, Chu Min-ha finds herself drowning in work.

An urgent call sends Song-hwa rushing to the hospital to tend to a young patient. Ik-jun receives a plea from a desperate father.

Put in a stressful situation, Jae-hak looks to Jun-wan for advice on the right thing to do. Ik-jun accidentally uncovers an extraordinary secret.

Ik-jun handles a sensitive request from the troubled wife of a patient. A sudden piece of news threatens Seok-hyeong's peace.

As doctors and as humans, the five friends each face a maze of life's questions and decisions as they figure out their next steps.