Lois and Clark dig deeper on Bruno Mannheim, starting with his connections to Hob's Bay Medical Center, while Jonathan and Jordan panic at home over Lois' dire diagnosis.

Superman and John Henry clash over how to handle Bruno Mannheim, while Lois worries over upcoming treatments and confides in Lana about her early courtship with Clark.

Clark helps Lois prepare for a procedure but must leave the boys with her to help John Henry and General Lane track down the Mannheims.

All of Smallville comes together to view a meteor shower, and Lex Luthor makes his move to take down Superman and Lois.

Lana and Sarah join the fight against Luthor; Jordan and Jonathan butt heads over a decision.

Lois helps throw Kyle and Chrissy an impromptu wedding that doesn't quite go as planned.

Luthor plans to move LuthorCorp to Smallville, but finds opposition in Lana.

Luthor challenges Lois to a live telecast debate, though not everything is as it seems; John Henry and Clark face a troubling possibility.

The Kents fight with everything they have as Luthor makes his final move on Smallville.