Jess LaCroix and his elite team of FBI Fugitive Task Force agents track a doctor who's deeply involved in a world of organized crime, drugs and lies, and is on the run after a phone call records him delivering his wife's fatal shot.

A single mother goes into a deadly rampage at a Public Defender's office, taking justice into her own hands after her son is given a harsh sentence for a petty crime. Also, Jess worries how his daughter Tali is handling life without her mother.

When a young man is traumatized by his experience surviving a mass shooting, and radicalized into becoming an anti-government terrorist, the team must act quickly to track him down before he can exact revenge on those he believes failed him.

Barnes goes on a dangerous undercover mission involving an ambitious gang leader who is plotting turf wars and massacres across the Bronx in a bid for more power.

When a military veteran suffering from PTSS snaps after the death of his brother in arms, the decorated sniper’s expert abilities push the team to their limits. Also, Crosby’s personal struggles bubble to the surface when the case begins to hit too close to home.

A cult leader and his most trusted followers go on the run after he orders the murder of his own family. As Jess and the team race to find them, they uncover the self-proclaimed prophet’s conman past.

After the disappearance of his daughter is ignored by local police, a Native American man decides to take matters into his own hands. When his search escalates to murder, the team must track him down before his crusade claims any more lives.

When a domineering man and his girlfriend embark on a terrifying multi-state killing spree, the team races to find a pattern behind the deranged couple's seemingly random acts of extreme violence. Also, Jess worries he's being left out of Tali's life when he finds out his daughter has already won an award at school.

After taking down a terrorist, the FBI and their Fugitive Task Force partners turn their attention to the terrorist’s wife who escaped with one million dollars and is determined to follow through with her husband’s deadly plan. Also, LaCroix’s daughter, Tali, is taken away by ICE, but as Jess tracks her down, he realizes her detainment may be more than just random coincidence.

The crossover starts on FBI S02E18 American Dreams (I).

After a former counter-intelligence officer is caught leaking classified information to a foreign government and attacks his former partners, the team must track him down before he escapes the country.

After a small town police officer claims he’s the victim of a deep-rooted conspiracy and begins taking revenge on those he believes are responsible for his downfall, Jess and the team find he just might be right, on the first of two new back-to-back episodes

After a manipulative student commits murder in a fit of jealousy, the team races to capture her before she escapes across the border. Also, Jess teaches Tali how to stand up to bullies, on the second of two new back-to-back episodes

When a case of cyber-stalking escalates to multiple murders, the team must track down a hacker who will stop at nothing to get revenge on those he believes have wronged him. Someone from Hana’s past offers her help on the case, but at a price she’s not willing to pay.

When a father and son bank robbing duo escape from a prison transport van on their way to trial and pick up where they left off, the team must hunt them down before they steal enough money to escape the country. Jess draws on his own personal history to profile the duo’s father-son dynamic.

With COVID-19 devastating the country, two gunmen take out their desperation and rage on the elite class they perceive to be oppressing them; Jess' father returns and may not be over his old ways.

When a hacker triggers a car crash that kills a family of three, the team races to hunt him down as his ransomware demands escalate and his final target becomes apparent.

After witnessing her husband's murder, a woman is kidnapped from her home along with a mysterious stash of money hidden in her floor. When Jess realizes there may be a connection to one of his past cases, the need to find the kidnapper becomes personal.

The team searches for a young woman who is heading down a deadly path of vengeance, using ties to an online radical conspiracy organization to further her cause. Also, Barnes must make a life-changing decision, finding it hard to not let the dark side of her job affect her.

After a rogue militia group opens fire on several teenagers crossing the Canadian border into the U.S., the team races to find the ringleader and his final target. Also, Jess' relationship with his father, Byron reaches a breaking point.

After a robbery gone wrong ends with a murder and kidnapping, the team races to rescue a mother and daughter whose abductors are not what they seem. Also, Crosby enters a new living arrangement.

After a suspect escapes trial and goes on a murder spree, the team partners with his bail bondsperson, Jackie, in order to track him down. Also, Jess continues to struggle with moving forward in his love life.

The team welcomes a new member as they begin their hunt for a repeat offender and the child he kidnapped after murdering the boy’s single mother. Also, Jess tries to move past the awkward exchange he had with Sarah during their last encounter.

The team chases an unlikely serial killer whose end game takes a shocking turn. Also, Hana returns from medical leave, and Jess and Sarah's relationship continues to evolve.

After Crosby's old army buddy is attacked in an apparent drug deal gone wrong, the team's quest for answers uncovers a dangerous web of conspiracy. Also, Jess questions his relationship with Sarah after an unexpected encounter.

After a double murder takes place in a small town, the team goes after the vigilante who relies on internet sleuths to exact revenge on suspects in the name of justice. Also, Jess and Sarah's relationship continues to grow, but not everyone approves.

When a young man accidentally shoots a cop in self-defense and goes on the run, the team members find themselves in a moral dilemma on the best way to carry out justice. Also, Barnes and her wife struggle with their plans to have another child.

The team tracks two brothers set on getting revenge against members of the company that caused their town's environmental destruction. Also, Sarah meets the rest of the LaCroix family, including Jess' sister, Louise.

The team heads to D.C. to protect Ortiz's former informant after a hitman tries to kill her. Also, Sarah helps Jess' family prepares for Byron and Marie's last-minute wedding on Jess' farm.

Jess and the Most Wanted team head to Tennessee to track down an undercover DEA agent who appears to have turned dirty amid a major drug ring operation. Also, Sarah wonders if it was a mistake to move in with Jess and Tali so soon.

A local FBI case involving two murdered women and a sea of powerful men turns into a manhunt for the dangerous leader of a far-reaching criminal enterprise.

The crossover starts on FBI S04E01 All That Glitters (I). It continues on FBI: International S01E01 Pilot (III).

New Fugitive Task Force member Kristin Gaines joins Jess and the team, as they head to D.C. to find a dangerous fugitive from the Jan. 6 Capitol riot

When a judge known for serving harsh sentences to juveniles is murdered, the team looks into his lengthy list of cases in the hunt for his killer. Also, Kristin faces family hurdles while resettling with her teenage daughter in New York City.

The team must determine if the kidnapping of a young Chinese-American woman is a random hate crime or if she was specifically targeted, in order to find her. Also, Jess and Sarah struggle with Tali’s continued rebellious streak.

After a deadly fire at an arcade, the team discovers the blaze was just the first step in an intricate plan to exact revenge on one of the victims. Also, Hana rejoins the team, finding new adjustments in all aspects of her life.

The team attempts to hunt down a family annihilator before he continues his murder spree. Also, Barnes’ intrusive mother puts pressure on her marriage.

The team investigates the murder of a professional basketball player’s wife, who was a famous lifestyle guru. Also, Kristin and her ex-husband grow closer, and Special Agent in Charge Isobel Castille checks in with the team on the high-profile case.

After a prized Kentucky racehorse is stolen and its groomer is taken hostage, the team quickly learns they may be the only ones who consider the young woman’s safety a priority over the horse’s. Also, Byron returns to celebrate the holidays with Jess and his family.

While holiday shopping, Barnes and Jess are caught in the middle of a mall shooting, with the exits rigged so no one can escape. Also, Gaines, Hana and Ortiz try to help from the outside, knowing their team's family members are inside and at risk.

The team hunts for a young man who is using napalm-style bombs to attack his targets. Also, with Tali away, Jess and Sarah begin to adjust to their empty nest.

The Fugitive Task Force chases a killer who plays a twisted game of cat and mouse with his victims. Also, Hana shares something personal about herself with her new roommate, Ortiz.

The team searches for a notorious Colombian drug lord after he escapes from a U.S. prison. Also, Kristin begins to open up to her ex-husband about her past.

The team searches for a businessman wanted for murder and an embezzlement scheme. Also, Jess takes advantage of his empty nest to properly court Sarah.

The team pursues an abusive man on the war path to find his ex-girlfriend, who is trying to escape him for good. Also, Jess and Sarah make plans to take their dream vacation together.

The team must track down a murderous member of the incel community targeting those he believes never give him a chance. Also, Barnes, Hana, Ortiz and Kristin deal with their grief in the wake of Jess’ death.

The team gets called to Vermont after a married couple who grow illegal marijuana massacres their employees. Also, Barnes begins to regret not taking any time off to bond with her new baby.

The team's new leader, charming but formidable Special Agent Remy Scott, takes charge as they investigate a series of homicides tied to a forbidden love between a young teen and her older boyfriend.

Remy and the team investigate the homicides of two Army veterans in a murder spree connected to their time in Afghanistan.

The team goes after the killer of a man in witness protection but finds there’s more to the case than meets the eye. Also, Remy is challenged by what he discovers when he reconnects with his mother, Betsy, in person.

The team searches for a murderer recreating the chilling killings of a notorious ‘80s mobster.

When a wealthy East Hamptons couple are killed by a female con artist posing as a personal trainer, the team works to find out her true identity and track her down. Also, Ortiz is put in a tough place when Hana's brother asks a favor.

The team chases an oligarch who goes on a terror spree in New York City in a desperate attempt to escape his impossible situation.