On 12 December 1985, Arrow Air Flight 1285, carrying troops of the US Army's 101st Airborne Division, stalls and crashes just seconds after taking off from Gander International Airport in Canada, killing all 256 people on board. The cause of the crash remains disputed.

On 22 December 1999, Korean Air Cargo Flight 8509, en route from London Stansted Airport to Milan, Italy, crashes into a field about 55 seconds after taking off, killing all four crew members on board. The causes of the crash were the captain following the indications of a malfunctioning attitude indicator and lack of communication amongst the crew members.

On 8 October 2001, Scandinavian Airlines Flight 686, carrying 110 people bound for Copenhagen, Denmark, is taking off at Milan's Linate Airport in thick fog. On the runway, it collides with an Air Evex business jet carrying four people bound for Paris, France. The airliner suffers major damage and crashes into a building shortly afterwards. All 114 people on board the two aircraft are killed, along with four on the ground. The crew of the business jet had made a wrong turn while taxiing in the fog and inadvertently taxied onto the runway.

On 25 January 2010, Ethiopian Airlines Flight 409, en route to Addis Ababa, plunges into the Mediterranean Sea shortly after takeoff from Beirut–Rafic Hariri International Airport during a thunderstorm, killing all 90 people on board.

On 16 July 1999, John F. Kennedy Jr. dies when the Piper Saratoga light aircraft he is piloting crashes into the Atlantic Ocean off the coast of Martha's Vineyard, Massachusetts, in hazy conditions. His wife, Carolyn Bessette-Kennedy, and sister-in-law, Lauren Bessette, are on board and are also killed. The NTSB concluded that the crash was caused by spatial disorientation resulting in pilot error.

On 3 September 1989, the pilots of Varig Flight 254 enter an incorrect heading into the flight computer. Instead of flying towards its destination, the aircraft flies west and after some time is over a remote area of the Amazon jungle. Attempts to reach an alternative airport are unsuccessful, and the aircraft eventually runs out of fuel. The pilot makes a belly landing in the jungle where 13 people die.

On 10 February 2011, Manx2 Flight 7100 crashes at Cork Airport in Ireland after the pilots lose control of the aircraft in an attempted go-around in low visibility. Six of the twelve people on board are killed in the crash.

On 7 March 2007, while landing at Yogyakarta at the end of a routine domestic flight from Jakarta, Garuda Indonesia Flight 200 hits the ground so hard that it bounces violently before running off the end of the runway, killing 21 of the 140 people on board.