Facing immediate danger from wild animals Senku and Taiju are forced to revive Tsukasa Shishio "The Strongest High School Primate". Although Tsukasa has tremendous fighting ability and provides abundant food as their hunter, their new ally harbors an opposing view on restoring humanity.

Taiju and Yuzuriha figure out Senku's secret to reviving him. But now that he's back, they need to deal with Tsukasa.

Senku continues in trying to advance the Stone World, this time he makes "space food", it is in actuality cup noodles. After Senku finishes his project, Gen has an epiphany and devises a plan to take down Tsukasa's army without violence.

Chrome must use all of his scientific knowledge to escape from his prison and save Senku and others.

The Final Battle for the miracle cave starts as Senku and the Kingdom of Science conduct a frontal assault on the cave.

The Kingdom of Science is victorious, however it is not over for Senku. Senku must use all of his knowledge to cure Tsukasa who is severly injured.

Kaseki's efforts to build the science vessel Perseus hit a roadblock when he realizes that it's impossible to get all the parts to fit in practice.

Kohaku has located the treasure left behind by Byakuya and the others, but it's encased in concrete. Senku has to devise a plan to quietly get at the contents inside, so as to not alert the guards.

The Kingdom of Science members launch an attack on the islanders aboard the Perseus, but Moz isn't far behind and Senku and the others are forced to retreat inside the vessel. Ibara has them cornered, but Senku unleashes his Joker card.

To the moon! That's the plan, at least. Senku and the Kingdom of Science need to devise a means with which to go to the moon and deal with Why-Man. The first step is allying with the people of Treasure Island and enlisting their help with some new crafts.