After the police ignore a desperate father's plea for help, he abducts a billionaire's daughter and holds her hostage in a near-impenetrable safe room until his own missing child is returned to him. Also, Jubal puts his hostage negotiation skills to the test.

As the team hunts a killer who is fatally shooting seemingly unrelated targets, an experience on the job has new agent Tiffany Wallace examining the tension between her career as an FBI special agent and the responsibility she feels to her community as a Black woman.

The team investigates a series of brutal assaults; OA hides information about his own mugging.

The investigation into an assistant U.S. attorney’s death leads the team to a related airline whistleblower scandal and the chilling discovery that they don’t have much time to thwart terrorists from crashing numerous in-flight commercial airplanes. Dealing with the memory of his brother, who was a 9/11 victim, the case pushes Scola hard to prevent another catastrophe.

When two IRS special agents are stabbed to death in Brooklyn, the team is thrown into an investigation that leads back to the resurgence of the online conspiracy community of Duke Ducoyle, their suspect from a previous case.