Helen takes the reins at NHS Hampstead Hospital while Max gets creative to help a patient in need. Reynolds reaches a decision about Dr. Malvo. Iggy and Bloom help their patients understand the underlying cause of their stress. Dr. Wilder employs more unconventional techniques.

When Helen Sharpe unexpectedly returns to New York, Max escapes to the wilderness on a corporate retreat with Bloom, Dr. Wilder and Iggy. Fun soon turns into catastrophe that threatens a life. Reynolds agrees to perform a risky surgery on a medical school colleague's young son only to be faced with unexpected challenges outside his control.