Vic consults an old friend for help with a major life change, Cliff takes his online habits too far, and Jane battles the “others” for Kay. Sensing imminent danger, Madame Rouge attempts to rally the highly distracted group.

With the end of existence imminent, a determined Doom Patrol seek to get their longevities back and save the universe.

After returning to Cloverton, the Doom Patrol gather for a final mission one that proves to be unlike any they've had before.