When her pilfered stash of pills runs out, troubled Annie tries to quit -- but ends up blackmailing her way into the Neberdine study.

After taking the B pill, Annie and Owen find themselves on 1980s Long Island entangled in a strange caper involving a lemur.

Azumi tells James the whole truth about the study's snags and urges him to call his estranged mother, an esteemed therapist.

Owen and Annie take the C pill. No longer connected, he belongs to a Mafia family, and she's a medieval guide hired by an ailing elf princess.

Annia and Ellia continue their quest, and Owen's mafioso father pressures him to protect the family. Greta counsels a bereaved Gertie.

After the subjects are discharged, James and Azumi face Neberdine's CEO. Owen and Annie part ways -- until a startling headline sparks a reunion.