Dr. Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join the prestigious St. Bonaventure hospital’s surgical unit. Alone in the world and unable to personally connect with those around him, his only advocate, Dr. Aaron Glassman, challenges the skepticism and prejudices of the hospital’s board and staff when he brings him in to join the team. Shaun will need to work harder than he ever has before, as he navigates his new environment and relationships to prove to his colleagues that his extraordinary medical gifts will save lives.

Dr. Shaun Murphy’s attention to detail complicates his first day at St. Bonaventure Hospital. Meanwhile, Dr. Claire Browne learns a valuable lesson about honesty when confronted with a difficult diagnosis for her patient.

Dr. Neil Melendez and Dr. Jared Kalu discover their patient isn’t being completely honest with them which may cost him his chance at a life-saving surgery. Meanwhile, Dr. Claire Browne must learn to communicate with Dr. Shaun Murphy as they race back to St. Bonaventure Hospital with a donated organ.

Dr. Neil Melendez and the team have to wade through legal waters when a husband and wife have to make a life-changing decision about their unborn child. Meanwhile, Dr. Shaun Murphy struggles to adjust to his new environment at home and makes a huge step forward with his colleagues.

While in the exam area of St. Bonaventure Hospital, Dr. Shaun Murphy encounters a young patient who looks eerily similar to his deceased brother, Steve. After discovering his parents have hidden his diagnosis from him, Shaun struggles to understand why he doesn’t deserve to hear the truth about his own health. Meanwhile, the team can’t figure out what keeps triggering their patients’ increasingly severe allergic reactions and races to find the cause before the next one kills another patient.

Dr. Shaun Murphy and Dr. Claire Browne devise an experimental procedure that can save the leg and life of a young groom, that is if his bride-to-be and parents can learn to work together. Meanwhile, Jared struggles to emotionally connect with his patient whose scars may prove too deep to overcome.

Dr. Shaun Murphy has to confront prejudice from an unlikely source when he takes on the case of a patient with autism, and Dr. Jared Kalu has to learn to accept his limitations as a surgeon.

During a robbery at the grocery mart Dr. Shaun Murphy is shopping at, his communication limitations puts lives at risk. Meanwhile, after Shaun's traumatic day, Dr. Aaron Glassman worries that he isn't doing enough to help Shaun.

As part of St. Bonaventure hospital's international humanitarian program, the team takes on the case of a young boy from the Congo who has severe congenital heart anomalies. Dr. Neil Melendez has doubts about the safety of the procedure, while Dr. Shaun Murphy works out the best course of action. Meanwhile, Murphy's latest encounter with his neighbor Lea has him confused.

A charming young doctor puts a member of the surgical team in an awkward position at work; Dr. Glassman suggests that Dr. Shaun Murphy meet with a therapist.

Dr. Marcus Andrews enlists Dr. Neil Melendez on a very sensitive kidney transplant between a pair of twins; Dr. Shaun Murphy decides to take an impromptu trip with his friend Lea and leave his problems behind.

The twins suffer complications from their surgery forcing the team at San Jose Boneventure Hospital to make a life-changing decision. Meanwhile, Dr. Shaun Murphy returns to the hospital after his trip with Lea and decides he needs a more permanent change and gives Dr. Aaron Glassman his two weeks’ notice.

Dr. Shaun Murphy suspects his patient is lying about the reason for her injury and makes a controversial assumption about her motives. Meanwhile, Dr. Neil Melendez’s personal life could be affecting his work and, ultimately, his patients lives.

Dr. Shaun Murphy is surprised to learn that his young cancer patient identifies as a girl while being biologically male. Shaun must quickly learn to understand his patient, her medical needs and how to work with her family, who all feel they know what is best for her.

Dr. Shaun Murphy's teenage patient has been confined to her home her entire life due to a rare heart condition. Despite her condition, she has cultivated a large group of friends online and hopes that the surgical team can find a way to give her the life she has always dreamed of having. Meanwhile, a young patient's perfectly matched organ donor is causing a moral dilemma for the parents and the patient.

When the team treats a patient who has to decide between a dangerous surgery that could change his life or remain the same, he asks Dr. Shaun Murphy what he would if he had that same choice.

Dr. Shaun Murphy questions the need for an elective surgery that will allow his young patient to smile for the first time. Meanwhile, Dr. Claire Brown and Dr. Morgan Reznick discover that their patient lied about her identity.

The team at St. Bonaventure needs to quickly discover the truth behind a young college student’s unexplained injuries before his condition worsens. Meanwhile, after losing his most prized possession, Shaun’s distraction during a surgical procedure may end up risking more than just his job.

Shaun’s proposed treatment for a homeless patient puts him and Dr. Kalu in Dr. Andrews’ crosshairs. Claire tries to overcome Dr. Melendez’s reluctance to do a risky heart operation. Dr. Glassman faces a difficult decision about his health.

As Shaun pushes back against Dr. Melendez in order to treat a gravely ill hospital janitor, Dr. Lim risks a lawsuit to repair a teenage girl’s ritual circumcision. Dr. Glassman exercises demanding oversight in choosing a doctor for his brain surgery.

Dr. Melendez, Dr. Brown and Dr. Park have given a young married couple two choices about their future: save the wife’s life or their future ability to start a family. Meanwhile, when Dr. Lim has to take care of some personal business, she leaves oversight of the emergency room to Dr. Murphy and Dr. Reznick; and Dr. Glassman’s post-op recovery leaves him struggling to get the rest he needs for recovery and also confronting his relationship with his daughter.

Shaun recalls his own past to help an intellectually disabled teenager face separation from his mother, while Claire is put between an injured teenage rock climber and her worried parents. Meanwhile, Glassman’s post-op hallucinations force him to confront a personal tragedy.

When a patient suffering from anorexia can’t gain the necessary weight needed to survive heart surgery, Claire suggests they perform an experimental surgery which Melendez strongly opposes. Shaun worries Glassman’s refusal to walk the hospital floor will keep him from being discharged and tries to persuade him to ambulate. Meanwhile, Shaun and Lea change the terms of their current relationship.

Morgan and Shaun’s indecision on how to treat a young violinist who visits the ER with an infected finger could affect her future in more ways than one. Meanwhile, Lim, Claire and Park can’t figure out if their young patient is really ill or looking for attention.

Dr. Shaun Murphy and Dr. Morgan Reznick must contend with two brothers who are bargaining over life and death. Meanwhile, Dr. Claire Brown’s friend who is dying of cancer asks her for something she doesn’t think she can give her; and Dr. Aaron Glassman is dealing with the effects of his treatment.

Dr. Shaun Murphy, Dr. Audrey Lim and Dr. Claire Brown’s E.R. patient is forced to reveal a secret to her husband after their treatment caused a complication. Meanwhile, Dr. Neil Melendez, Dr. Morgan Reznick and Dr. Alex Park struggle with a patient whose parents don’t believe in vaccinations.

Dr. Neil Melendez, Dr. Morgan Reznick and Dr. Claire Brown grapple with a patient’s wish to perform an operation that would keep him from acting on his pedophilic urges; and Dr. Shaun Murphy learns a lesson in empathy.

Dr. Shaun Murphy and Dr. Alex Park treat two patients who collapse at the local airport and whose symptoms point to an infection that may become airborne. The staff races to contain the infection before it spreads to the rest of the patients in the ER, resulting in a hospital quarantine during the holidays.

The hospital is still in quarantine as Dr. Shaun Murphy continues to be overwhelmed by the chaos and noise in the emergency room; Dr. Morgan Reznick struggles to keep her patients alive, and Dr. Audrey Lim fights for her life. Meanwhile, Dr. Neil Melendez and Dr. Claire Browne must find a way to complete their patient’s bone marrow transplant, despite the quarantine.

In the aftermath of the quarantine, the staff tries to return to their normal routines. Meanwhile, as Dr. Lim recovers from the virus, she and Dr. Melendez navigate their new personal and working relationship, while Dr. Murphy and Dr. Glassman visit Lea.

Dr. Shaun Murphy, Dr. Morgan Reznick and Dr. Audrey Lim treat a woman with autism and a delicate brain condition while navigating the complicated relationship she has with her roommate, who is also on the spectrum. Meanwhile, Lea and Shaun are still figuring out their friendship and roommate status.

Dr. Andrews tries to convince a grieving family to donate their teenage daughter’s face to another young girl whose face was horribly disfigured in an accident.

Shaun’s blunt honesty with a distraught mother of a critically ill newborn baby causes the new chief of Surgery to question keeping him on as a resident.

The new chief of surgery, Dr. Jackson Han, believes Dr. Shaun Murphy is a liability more than an asset and works to keep him out of the operating room permanently.

Dr. Shaun Murphy is desperate to join the team on a dangerous procedure involving a patient’s tumor removal. However, having been removed from the surgery team by Dr. Jackson Han, Shaun must use his talents to help figure out the cause of an infant’s injuries.

As a barroom fight sends Dr. Shaun Murphy to seek treatment at St. Bonaventure’s, Dr. Alex Park and Dr. Audrey Lim disagree over an elderly woman’s post-operative symptoms. Meanwhile, Dr. Neil Melendez and Dr. Lim make their romance public, and Dr. Aaron Glassman continues to pursue a relationship with a good friend.

Dr. Shaun Murphy proposes a radical surgery to save a woman's life after what he believes was a disastrous first date with Carly. Meanwhile, after the new chief of surgery, Dr. Audrey Lim, announces that the residents can lead surgeries, Dr. Morgan Reznick and Dr. Alex Park compete for the chance to operate on an elderly patient who has been diagnosed with cancer.

As Dr. Marcus Andrews vows to help a good Samaritan who was injured while stopping a sexual assault, Dr. Audrey Lim faces a difficult decision when a young patient’s parents suspect that Dr. Neil Melendez made a mistake. Meanwhile, Dr. Shaun Murphy fields advice following his disastrous date with Dr. Carly Lever; and Dr. Claire Browne gets a surprise visit from her mother.

Dr. Claire Brown faces complications at home and work as she prepares to lead her first surgery. Meanwhile, a sports fishing accident challenges the rest of the staff as they look to treat the fisherman’s injuries without damaging his prize catch.

As a conspiracy theorist questions Dr. Neil Melendez’s diagnosis, Dr. Claire Brown treats a woman whose inability to feel pain is threatening both her marriage and her life. Meanwhile, Dr. Shaun Murphy and Dr. Aaron Glassman each face crises in their romantic relationships.

Dr. Shaun Murphy has been assigned his first surgery by Dr. Audrey Lim. However, Dr. Marcus Andrews questions whether he is really ready. Meanwhile, as Dr. Claire Brown continues to avoid her complicated emotions about her mother, she and Dr. Morgan Reznick have a patient whose diagnosis has them doubting his story.

While performing his first solo surgery, Dr. Shaun Murphy alienates a nurse, which puts his residency in jeopardy. Dr. Neil Melendez disagrees with Dr. Audrey Lim on a risky surgery. Dr. Claire Brown spirals into self-destructive behaviors, causing negative ramifications in the workplace.

Dr. Shaun Murphy’s unique ability to relate to a patient isolated by an immune deficiency yields an unexpected result. Meanwhile, Dr. Claire Browne, Dr. Morgan Reznick and Dr. Marcus Andrews treat a 12-year-old patient who is about to become blind, and tension builds between Dr. Neil Melendez and Dr. Audrey Lim.

Carly’s attempts at increasing her intimacy with Shaun are becoming more of a frustration than either of them expected. Meanwhile, Lim and Melendez struggle in their relationship as they work to separate their work from their personal life.

Shaun is ready for the next step in his relationship with Carly; however, he continues to struggle as they grow closer and more intimate, and is dealt some troubling news about a deeply personal issue. Meanwhile, a young patient must decide on a treatment that could save her life or possibly destroy her marriage.

Shaun visits his father on his deathbed and the family reunion reveals unexpected results. Melendez, Park, Reznick and Claire treat an injured star NFL player with severe spinal damage. Claire addresses her mental health.

Following his father's death, Shaun must deal with the effects his intimacy with Lea will have on his relationship with Carly; the team operates on a patient who is refusing all anesthesia during surgery for fear of relapsing.

The doctors must treat a 25-year-old runner who is suffering from severe swelling; two 16-year-old cancer patients are dating; Dr. Shaun Murphy and Dr. Carly Lever work toward intimacy.

A terminal cancer patient is determined to live the last few months of his life without inhibition; Dr. Reznik must confront her relationship with her mother when she comes in for a third opinion from Dr. Glassman.

After Dr. Shaun Murphy treats a patient who is a social influencer, he deals with unwanted attention. Meanwhile, the team treats a woman who is in abdominal distress after an at-home fecal transplant; and Dr. Carly Lever’s efforts to separate Shaun from Lea are challenged.

Despite everyone else’s doubts, Shaun is hopeful that Carly is truly fine with his friendship with Lea. The team treats a young boy born without a fully formed trachea and unable to speak, and who may be a good candidate for an experimental procedure.

When Dr. Shaun Murphy makes an emotional confession, the result may not be as desired. Meanwhile, he becomes obsessed with performing an autopsy on a Jane Doe, which challenges his relationships at the hospital; and Dr. Claire Browne, Dr. Morgan Reznick and Dr. Marcus Andrews treat a male college student with a mysterious split personality disorder.

A patient with a mysterious and undiagnosed illness that has baffled other doctors for years forces Shaun and the team to take some big risks. Claire and Melendez continue to cautiously navigate their feelings for each other as colleagues and friends.

Claire and Shaun treat a patient with a rare form of dwarfism. Reznick, Lim and Park treat a young man who had both arms torn off in a previous farming accident. Shaun reacts to an emotional situation.

The city of San Jose is rocked by a massive earthquake that puts the staff of St. Bonaventure Hospital on high alert as they race to assess the damage and account for the safety of their colleagues and friends. Meanwhile, Dr. Neil Melendez and Dr. Aaron Glassman are attending a charity event when their lives are threatened by the earthquake.

The staff of St. Bonaventure Hospital works against time and their own personal safety to save the lives of those around them.

Covid-19 vīrusam izplešoties, visa komanda komanda turpina srādāt, lau glābtu dzīvības.

Astoņas nedēļas pēc Covid-19 uzliesmojuma sākuma, komanda svin mazās uzvaras, bet cieš vēl vienu milzīgu zaudējumu.

Vairāki kandidāti pretendē uz rezidentūru slimnīcā. Lima liek Šonam, Klērai un Aleksam mentorēt pirmā gada rezidentus.

Morganas un Šona paciente, grūtniecei ar dvīņiem, izjūt sāpes, liekot ārstiem izdarīt lēmumu, kuru neviens nevēlas pieņemt. Šons lūdz, lai Lea pārceļas atpakaļ.

Ašers cīnās ar vainas apziņu, kad nosaka nepareizu diagnozi savam pacientam. Pārks un Morgana izveido negaidītu saikni, bet gandrīz letāla avārija satricina Glāsmanu un Debiju.

Odrija cenšas tikt galā ar Covid-19 radīto emocionālo traumu. Klēra ierosina radikālu ārstēšanas metodi, lai palīdzētu kara veterānam. Šons paziņo, ka vairs nevēlas mācīt jaunos rezidentus.

Šons uzzina pārsteidzošu patiesību par Lea. Tikmēr komanda ārstē divus pacientus ar sarežģītu personīgo dzīvi.

Šons gatavojas tikties ar Lea vecākiem. Tikmēr slimnīcas komanda ārstē elites vingrotāju un viņas treneri, kurš ir arī viņas tēvs.

Kamēr komanda ārstē divus pacientus ar sarežģītu vēsturi, Klēras un Limas attiecībās saasinās. Šonam iepatīkās jaunā kolēģe.

Morganai neizdodas atrast aknu donoru sievietei ar Dauna sindromu. Amputētam triatlonistam jāveic riskanta operācija, lai viņš varētu turpināt vākt naudu vēža izpētei.

Glāsmans izdomā jaunu procedūru, lai palīdzētu jaunietim ar deformētu mugurkaulu. Tikmēr Šons un Morgana cenšas izlemt, ko darīt, kad komā nonākušais pacients atgūst samaņu.

Meklējot palīdzību, Sv. Bonaventūras slimnīcā ierodas īgns ķirurgs ar diagnozi, kas varētu beigt viņa leģendāro karjeru. Pārks un Morgana nav vienisprātis par pacienta hronisko sāpju cēloni.

Negaidīts viesis liek Klērai pārdomāt savu pagātni, bet reta slimība nostāda profesionālu balles dejotāju pāri grūtas izvēles priekšā. Leas pārdomas par grūtniecību atklāj plaisu attiecībās starp viņu un Šonu.

Tiek atklāts gaidāmā bērna dzimums un Leas entuziasms liek Šonam saņemties un sniegt lielāku atbalstu.

Politisks protests kļūst vardarbīgs un tiek sašauti divi jauni cilvēki. Komanda cīnās, lai glābtu cietušos.

Sarežģījumi Leas grūtniecība ietekmē Šonu. Ašers cenšas izpildīt pacienta pēdējo vēlēšanos.

Šons riskē ar savu karjeru, apstrīdot slavena ķirurga un Endrjūsa bijušā mentora darbu. Klēra un Morgana nespēj vienoties par kāda ievērojama ASV senatora sejas krampja cēloni un ārstēšanas metodi.

Negadījums pārgājiena laikā liek Lea pieņemt dqramatisku lēmumu. Lima cenšas pārliecināt divus vecākus atļaut operēt viņu meitai, bet Morgana nespēj vienoties ar pacientu.

Ārstu komanda no Sv. Bonaventūras slimnīcas dodas palīdzības misijā uz slimnīcu Gvatemalā.

Sv. Bonaventūras komanda dodas palīdzības misijā uz Gvatemalu un stājas pretī virknei izaicinājumu.

Šona un Leas gaidāmā saderināšanās ballīte visiem rada svētku noskaņojumu. Jauna vientuļā māte uzzina, ka viņas dēls, iespējams, ir inficējies ar vēzi.

Dr. Šons Mērfijs un komanda cenšas palīdzēt grūtniecei un glābt viņas bērnu. Situāciju un komandas centienus sarežģī fakts, ka sieviete ir notiesāta noziedzniece.

Salenas jaunās vadlīnijas rada šķēršļus diviem pacientiem, kuriem nepieciešamas dārgas operācijas. Negaidīts Šona ielūgums Lijai rada kāzu plānošanas grūtības.

Salens uzstāj, ka viņa meitas medicīniskajā aprūpē jāņem vērā tēva interneta pētījumi. Mirstoša sieviete vēlas atjaunot saikni ar savu dēlu.

Dr. Pārks un Dr. Mērfijs ārstē vecāka gadagājuma aziātu izcelsmes vīrieti, kas ir rasu naida nozieguma upuris. Lea slepus no Šona palīdzētu uzlabot viņa pacientu apmierinātības rādītājus.

Dr. Šonam Mērfijam un dr. Aleksam Pārkam ir jāizlemj, vai glābt viena vai otra pacienta dzīvību. Dr. Morgana Reznika, mēģinot iegūt Salena labvēlību, savā rīcībā iet mazliet par tālu.

Šons un Lea kļūst par lieciniekiem šausmīgai autoavārijai, kurā ir smagi ievainota grūtniece, kurai nepieciešama tūlītēja medicīniskā palīdzība.

Šons ir spiests konfrontēt Lea par viņu attiecībām un noskaidrot, ko viņš viņai patiesībā nozīmē. Komanda apspriež plastisko ķirurģiju. Lims cer atklāt Salena piesegšanu saistībā ar zīdaiņa nāvi.

In an effort to please Salen, Andrews takes on a high-profile case and assigns Shaun and Allen to help perform a risky surgery to restore the voice of a famous pop star.

Uzzinot, ka ķirurģijas nodaļas personāls ir pievienojies Lima pret viņu vērstajiem centieniem, Salena krasi rīkojas. Komanda ārstē aknu transplantācijas pacientu, kura orgānu donors neapzināti ir izraisījis viņam vēzi.

Dr. Šons Mērfijs izveido personisku saikni ar pārgurdru jaunu pacientu, kas apšauba viņa objektivitāti.

Tā kā sievietes plaušu slimība viņai un viņas līgavainim rada negaidītas problēmas, koledžas profesoram ir jjāuzveic apkaunojoša slimība, lai viņa varētu sasniegt svarīgu dzīves mērķi.

Šons iestājas par pusaudzi, kura bioloģiskā uzlaušana ir apdraudējusi viņa rokas funkcijas. Morgana cīnās, lai saņemtu atļauju ārstēt pacienta depresiju, veicot radikālu smadzeņu operāciju.

Kad pēc kopā sanākšanas ķirurģijas nodaļas personāls cieš noslēpumainām halucinācijām, Šons un Glasmans sastrīdas, cenšoties novērst resursu nelietderīgu izlietojumu.

Lea izmanto savas vecu automašīnu labošanas iemaņas, lai salabotu pacienta dzelzs plaušu. Endrjūsa cenšas palīdzēt vardarbības upurim ar disleksiju, bet Džordana noraida Glāsmena ieteikumus par naudas piesaisti.

Šons atklāj kļūdu, kā rezultātā viņam jāveic apdegumu upurim otra sāpīga operācija. Parks cenšas palīdzēt nopietni ievainotam ugunsdzēsējam atgūt veselību un atgriezties darbā.

Kamēr Šons un Lea mēģina vienoties par savu kāzu tematiku, darbinieki mobilizējas, lai veiktu trīs riskantas operācijas kādam desmit gadus vecam zēnam no Gvatemalas.

Šons un Lea pieņem svarīgu dzīves lēmumu un ir patīkami pārsteigti par atbalstu, ko viņi saņem no saviem draugiem slimnīcā. Ašeram ir grūti pieņemt, ka viņš un viņa tēvs, iespējams, nekad īsti viens otru nesapratīs.

Šona un Leas ilgi gaidīto kāzu pieņemšanu pārtrauc vardarbīgs uzbrukums slimnīcā, un visai komandai jāmobilizējas, lai glābtu upurus.

Dr. Mērfijs un Dr. Pārks satiekas ar rezidentiem, kurus viņi pārraudzīs; Lima atgriežas darbā, saskaroties ar savu jauno realitāti un emocijām, kas saistītas ar izmaiņām.

Daktere Odrija Lima ir apņēmības pilna noskaidrot, kas īsti notika operācijas laikā, un sāk savu iekšējo izmeklēšanu.

Komanda strādā ar militāru notikumu atjaunotāju, kura autentiskuma pārbaudes mēģinājums ir radījis sprādzienbīstamu situāciju; Dr. Džordans Alens un Dr. Daniels Peress meklē nogrieztu pēdu, un laika ir pavisam maz.

Šons, Ašers un Pauels Helovīnā ārstē kādu jaunu pacientu, kuram ir reta iedzimta slimība, ar kādu ārsti iepriekš nav sastapušies.

Karstuma viļņa uzplūdā Dr. Šons Mērfijs un Dr. Danika Pauela nespēj panākt kopīgu viedokli par viņu pacienta operāciju.

Kad slimnīcā ierodas sieviete, kas gaida sešīšus, doktoram Markusam Endrjūsam ārsti jāsadala komandās, lai nodrošinātu, ka pēc augsta riska dzemdībām visi ir veseli un drošībā.

Dr. Šons Mērfijs, Ašers Volks un Glāsmens satiek pacientu ar inficētu ķirurģisko sūkli, kas atstāts viņa vēderā. Tikmēr Dr. Morganai, ārstējot seksuālas vardarbības upuri, jāsaskaras ar savu pagātni.

Dr. Šons Mērfijs, ieviešot jaunu darba vērtēšanas sistēmu, neapzināti rada konkurenci starp Daniku Pouelu un Danielu Perezu. Tikmēr Dr. Morgans Rezniks, iespējams, ir pārkāpis robežu attiecībā uz Dr. Aleksu Pārku.

Šons un Lea drīz uzzina, ka Leas negaidītā grūtniecība var būt ar papildu sarežģījumiem.

Lea un Šons, steidzot palīgā ievainotam sunim, ātri apgūst bērnu audzināšanas mākslu. Tikmēr ārste Danika Pauela slepeni veic draugam operāciju, kas varētu apdraudēt viņas karjeru.

Šons aicina Āronu palikt kopā ar viņu, kamēr viņa mājā ir kaitēkļu iznīcinātāji, un Lea saprot, ka abiem vīriešiem ir daudz vairāk kopīga, nekā viņa saprata.

Šons un Lea nevar vienoties par kopīgu audzināšanas stilu un uztraucas par to, kas notiks ar viņu attiecībām, kad piedzims viņu bērns.

Kad ātrās palīdzības nodaļā tiek nogādāts 3 gadus vecs bērns, ārsti uzreiz saprot, ka viņam ir insults. Tomēr Dr. Šona Mērfija pamatcēloņa diagnoze neatrisina problēmu, tāpēc Dr. Parks veic padziļinātu izpēti.

Dr. Džareds Kalu negaidīti atgriežas Sanhosē St. Bonaventure slimnīcā kopā ar savu pacientu, kurš ir miljardieris. Parkam ir jāarstē vīrietis, ar kuru viņa sievai bija romāns, un jāmēģina atrast veidu, kā viņam piedot.

Dr. Šons Mērfijs meklē juridisko pārstāvi, kas varētu palīdzēt viņam uzvarēt lietu, un uzticas daudzsološajam, jaunajam juristam Džonijam DeGrūtam, kuram ir obsesīvi kompulsīvi traucējumi.

Dr. Šonam Mērfijam atkal jāiemācās sadarboties ar dr. Džeredu Kalu un jāatgādina viņam, ka viņam St. Bonaventure viss jāsāk no sākuma. Tikmēr dr. Mērfijs ārstē pusaudzi, kas cieš no neiroloģiskiem traucējumiem.

Kad ierodas kāda paciente ar pastāvīgiem un ilgstošiem Covid simptomiem, komanda atklāj, ka viņai, iespējams, ir kas grūtāk ārstējams.

Dr. Endrjūss un Dr. Lima sastrīdas par gandrīz uz pusēm sadalītu pacientu, kas arī atklāj viņas problēmas saistībā ar Dr. Kalu atgriešanos. Tikmēr dr. Glāsmens sniedz dr. Mērfijam tēvišķus padomus.

Dr .Markuss Endrjūss iepazīstina dažus komandas biedrus ar pacientu, kura optimisms un ticība, ņemot vērā viņa attiecības ar reliģiju, šķiet, izraisa vislielāko skepsi.

Saspringtas situācijas rezultātā var neatgriezeniski sabojāties Dr. Glasmena un Dr. Mērfija attiecības, savukārt dr. Reznikai grūtības rada viņas bērna kopšanas atvaļinājums, un viņai visnoderīgākā var būt dr. Pārka.

Šons un Lea dodas uz dzemdību zāli, un tur ir arī visi slimnīcas pārstāvji, izņemot kādu ļoti svarīgu cilvēku. Tikmēr notiek traģisks negadījums.

Shaun and Lea adjust to parenthood as they debate the importance of schedule and routine for Steve. Meanwhile, Shaun takes on his first case back at the hospital with two baby patients in need of the same heart.

Shaun struggles to accommodate the newest member of his surgical team, Charlie, who interferes in a patient’s relationship with his daughter. Elsewhere, Park tackles a tricky brain tumor, and Lea and Morgan adjust to motherhood.

Shaun continues to be tested by Charlie when their newest case prompts her incessant stream of questions – all in pursuit of an answer. Meanwhile, Morgan struggles on who to name as guardian for Baby Eden should anything happen to her.

Shaun and Lea struggle to balance their parental duties with their personal lives. Meanwhile, Park and Morgan try to find the time and space to reignite their romance amidst the demands of parenthood and work, and Lim's mother makes a surprise visit.

Asher's views on the construct of marriage complicate his future with Jerome. Meanwhile, Asher also briefly revisits his religious past to aid a patient's conversion to Judaism for his fiancée.

The team must deal with a mass casualty event that forces them to put aside their emotions following a recent tragedy.

Shaun and Jordan's patient is in dire need of a kidney transplant. When they find the perfect donor, they also discover that he believes he is Jesus which could compromise his ability to give consent to the surgery.

Shaun, Jared and Charlie's young patient need his parents to agree on an important medical decision that could greatly improve his health; however, his parents are unable to agree on the correct path which spurs the team to try and intervene on behalf of their patient.

Dr. Claire Browne returns from her work in Guatemala for a personal medical examination. Elsewhere, Dr. Glassman struggles to manage Hannah, who remains unresponsive to his attempts to help. Park seeks out the perfect last-minute wedding location.

As the doctors consider their futures, they work together to solve one of the most important cases of their careers.