Paul begins to suspect that Susan is responsible for his rapidly declining health; Lynette and Tom butt heads over where to go on their family vacation, as well as which one of them will set it up; Gaby shows Juanita a horror movie and has to pay the price when her daughter becomes too scared to sleep in her own bed; and Bree runs into some trust issues when she goes out on a date with a detective.

A progressive dinner party thrown for Susan to celebrate her move back onto the lane leads to a shocking murder. Meanwhile, Gaby is stunned to learn the identity of the mysterious man who has been stalking her; Lynette and Tom attempt to put the spark back into their marriage by spending a few days alone together at a romantic Bed & Breakfast; after being placed under arrest for allegedly poisoning Paul, Susan must convince the police that she was being framed for the deed by Felicia; Bree begins to suspect that her new boyfriend may be gay.

The Wisteria Lane residents each enjoy a progressive dinner; Renee begins a short-lived relationship with a bartender; Bree sees a connection with Chuck; the housewives cover up a fatal accident.