Driven by a hidden agenda, Dave convinces Susan to throw Mrs. McCluskey a surprise party for her 70th birthday. Jackson wants to take his relationship with Susan to the next level. Gabrielle's concerned she might be pregnant. Tom tells Lynette he's sold the pizzeria. A startling reason for the bond between Bree and Katherine is revealed. And finally, an outraged Mrs. McCluskey has the entire neighborhood questioning her sanity.

In the aftermath of the plane crash, the residents of Wisteria Lane think about what their lives might have been like had they made different choices. Susan contemplates a life with Karl had she not left him. Bree considers life without Orson. Lynette thinks about a future with her unborn twins. Carlos reflects on how Gaby would be as an over-protective mom and Angie ponders the consequences should her secrets be revealed.