Holmes and Watson travel to Sussex to investigate the murder of Squire Douglas, who was shot to death in a sealed-up castle, with only two apparent suspects.

When Dr. Watson thinks that he has seen a ghost, it puts Sherlock Holmes on a trail that leads to a crime at an art museum.

Dr. Watson accidentally comes home from his club with another man's coat, providing an important clue when the other man is murdered late that same night.

The only clue at the site of two grisly murders is a chicken's foot. Baffled, Insp. Lestrade goes to Sherlock Holmes for assistance.

Vaudeville escape artist Harry Crocker turns to Sherlock Holmes for help when he is accused of strangling a chorus girl.

Sherlock Holmes investigates a strange story told to him by a shopkeeper, who claims to have been a member of the 'League of Red-Headed Men' until it unexpectedly dissolved.

Sherlock Holmes helps one of Dr. Watson's old friends by explaining the source of an odd noise in the man's home, but in doing so Holmes uncovers a more serious mystery.

Holmes and Watson are called to a boy's school in Belgium. It seems that a young student has gotten into the habit of writing the names of faculty members on the steps of a nearby church, and shortly afterwards person whose name has been written down is found dead.

A baby is left on Holmes' and Watson's doorstep. The child turns out to be the son of a missing French scientist. When Watson is later brutally attacked and the baby kidnapped, the detectives must find the baby and its father and avoid an international scandal.