Venice is facing an uncertain future as it deals with increasingly higher tides blamed on climate change. Anderson Cooper profiles the Oscar-nominated actor from the controversial film Joker and gets a rare interview with his family. The world's # 1 tennis player, Rafael Nadal, takes Jon Wertheim back to his hometown on the beautiful Spanish island of Mallorca.

Secretary of State Antony Blinken; a shortage of semiconductors reveals the U.S. is increasingly trailing behind Asia in the key sector; a book tells the story of doctors and scientists who saw the pandemic coming and tried to sound the alarm.