Dr. Manning and Dr. Charles assist in a complicated case helping a 4-year old who they quickly learn is no stranger to the ED. Dr. Marcel and Dr. Choi tend to a police officer with a mysterious gunshot wound to the abdomen. Relationships are put to the test as secrets are revealed.

Dr. Crockett is visited by two New Orleans detectives who have questions about his past. Dr. Choi puts his life in danger to save a child. Dr. Charles gives fatherly advice to his young daughter.

The staff adjusts to the new normal of the pandemic. Dr. Choi, Dr. Lanik and April fight on the front lines. Dr. Halstead and Hannah face a troubling reality. Dr. Charles tries to clear the air with his daughter following recent developments.

Goodwin announces a new ED Chief and the choice doesn't make everyone happy. Dr. Manning takes a stand for her patient and finds herself dealing with the repercussions. Dr. Charles tends to family affairs.

Dr. Halstead finds continued success in his trial. Dr. Charles' daughter, Anna, receives life-changing news. Noah finds himself in a situation not even April can fix.

Dr. Choi helps a patient with chronic pain find a solution. Dr. Halstead considers a new path. Dr. Charles and Anna bond over a scary situation.

Ethan hires an old Navy colleague to join him in the ED. A final custody hearing threatens to separate Charles and his daughter. Maggie must make a choice that will change Auggie's life.

Dean and Ethan respond to a scene that brings back some bad memories. When Carol's condition worsens, Natalie is willing to do whatever it takes to get her mom feeling better.

Dylan and Ethan treat a patient shot during a drug raid. Charles and Vanessa work together to properly diagnose a motivational speaker. Will and Hannah must turn to Crockett for help with a patient who's pregnant.

Halstead and Asher clash over a patient in need of a kidney transplant. Marcel faces a tough decision when Blake is in surgery. Choi and Archer treat the son of Med's general counsel. Med's family grows.

A documentary crew visits Med to film Marcel and Abrams' groundbreaking surgery. Archer refuses to ask for help for his kidney issues despite the staff's unrelenting kindness.

Maggie and Frost fight to get a pair of lungs for a young cystic fibrosis patient. Asher learns whether she can become a surrogate. Ripley and Morris treat a tech billionaire's daughter as she battles leukemia.

Goodwin is tasked with enforcing difficult cuts to hospital personnel. Charles' daughter is hospitalized after a car accident. A transplant patient makes a life-changing decision.