Peggy moves to the City of Angels to help Chief Daniel Sousa at the West Coast Strategic Scientific Reserve (SSR) investigate a bizarre homicide involving an alleged killer and Isodyne Energy, and reunites with some familiar faces.

Peggy and Sousa propose a trade with Whitney Frost, while the SSR gets help from Howard Stark that may be the key to eliminating Zero Matter.

Peggy needs Howard Stark to eliminate Zero Matter as they are faced with a mission none of them could come back from.