Jane and Rafael try to be friends which works great until Jane goes on a date. Petra and Jane's new partnership is off to a rocky start, but they both know they have to find a way to work together somehow. Rogelio is convinced he has Male Post-Partum Depression, which puts him at odds with with celebrity Post-Partum Advocate River Fields. Meanwhile, Alba finally tells Jane why she turned down the marriage proposal, leaving Jane to help Alba in the romance department.

When Jane, Rogelio and Alba learn what is going on with Xo, they all try to comfort her, but Xo insists they let her live her life. Rogelio finally gets River Fields to agree to meet with him, but he learns that River has another plan in mind. Rafael is on a mission to find his sister who may have the information he has been looking for. Meanwhile, Jane is upset with Petra after her girls spill a secret to Mateo.

Jane and Rafael find themselves in a not ideal living situation in order to save money. When Rafael sees Alba try to punish Mateo, an unexpected rift is formed. Xo tries to stay positive during treatment and even makes a new friend, but things get a little too real for her and Rogelio. River and Rogelio once again are at odds over their ideas for the show, but an unlikely person helps River see the show in a different light. Meanwhile, Petra feels unsupported by JR when she questions what really happened the night Anezka died.

Jane believes she and Rafael are in a good place until she realizes he is keeping a secret from her. Alba's big day has finally arrived, and Jane, Xo and Rogelio are ready to celebrate but Alba has other plans. Petra and JR make a decision about their future that neither of them saw coming. Meanwhile, River spends the week with Rogelio in order to help them be believable as a married couple, but she soon starts to take her role too seriously.

With Jane’s Catholic guilt starting to settle in, she turns to Alba for advice and gets an unexpected answer. Luisa decides to go see Rose with Rafael by her side, in order to help get answers. Meanwhile, Rogelio is back to work with River, but a power struggle ensues between the two and Xo might be the solution they have been looking for.

Jane must get over the newest hurdle in her life, which proves to be harder than she and Rafael would have hoped. Rogelio discovers that he and River are not as equal as he thought. Meanwhile, Jane and Petra must deal with the children not getting along with each other, which in turn brings up issues of how Petra and Jane feel about each other.

When Jane and Rogelio join forces to pitch a pilot, Jane is excited until she discovers a secret about her book being published. Alba and Jorge make an important decision about their future together. Rafael asks Jane to allow Luisa to meet Mateo, but she is unsure of her decision. Meanwhile, Petra and JR's relationship is once again tested.

When Rogelio tells Jane that the network wants her to write the script for their telenovela, at first she is excited, but begins to struggle balancing her time between that and her novel. Rafael is furious with Jane after she makes a medical appointment that he doesn’t agree with behind his back. Meanwhile, Petra tries to be positive about their relationship when JR lands a job interview out of state.

With Jorge officially moved into Alba’s house with his stuff, it quickly has changed the dynamic, making Jane to uncomfortable. Rafael and Jane work on their co-parenting of Mateo now that they have a potential way to help Mateo. Rogelio has a new set of unexpected problems arise on set with River. Meanwhile, Xo is nervous about her last PET scan and what the results could show.

After Rafael witnesses Mateo’s behavior at school, he wants to take a different approach to his treatment. Rogelio is paranoid that River is plotting her revenge against him. Meanwhile, Jane convinces Petra to go on a single ladies’ night out after she learns that Rafael is dating.

After Jane is struck with inspiration for her book, she immediately begins to write, but her next challenge is to get an agent. Rogelio has been so focused on being the star, he begins to contemplate taking on a different role instead. Meanwhile, Jane thinks it’s important to build a different relationship with the twins and turns to Petra for some guidance.

When Jane’s editor pitches her a dark twist for her book, Jane begins to wonder if the same thing might have actually happened to her. Rogelio helps River bond with her daughter, but River once again makes things difficult for him. To avoid thinking about her career change, Xo instead focuses on trying to smooth things over between Jane and Alba. Meanwhile, Alba stands up to someone from her past, which helps Jane realize she should do the same for herself.