The United States debates enacting a “render safe” mission to secure nuclear weapons that belong to the Pakistani government before it collapses, while the Murphy Station pursues the terrorist Jibral Disah.

After U.S. environmental activists protesting China’s damage of a South China Sea reef are arrested for spying, Elizabeth finds herself in a stalemate with the Chinese foreign minister as she lobbies for their release.

When the Mongolian government sends Elizabeth a horse as a gift, she thinks accepting it could upset other Asian countries, but she stirs up more controversy when she considers returning it to Mongolia. Also, Gov. Sam Evans threatens to sue Ohio for putting President Dalton on the election ballot, and Stevie has an interesting first day as Russell’s new intern.

When Elizabeth and her staff fly to Africa to offer development aid to the continent, they are caught by surprise when the Chinese arrive there first, ready to outmaneuver the U.S. with competing offers of aid. Also, when turbulence on their plane ride to Africa leaves Daisy unnerved, she and Susan Thompson go on a welcome tour of Africa, admiring the beauty of the continent. And, the FBI asks Henry to help investigate a Christian cult member who may have helped build the bomb used in the Illinois coffee shop attack.

Elizabeth’s landmark global climate treaty with more than 200 countries is jeopardized when China threatens to back out due to her meeting with an ailing Dalai Lama. Also, Henry worries about his undercover operative’s safety, and Jay is surprised when Abby serves him with a custody agreement for their daughter.

Elizabeth and her team work to secure the release of an American journalist held hostage in the Sudan.

When the assistant vice minister of Timor-Leste suddenly dies during a meeting with Elizabeth on the first day of the U.N General Assembly, she becomes suspicious after the president of Timor-Leste ships the body back without a proper investigation. Also, a “fake news” story surfaces claiming Elizabeth is responsible for the minister’s death, and Dmitri returns to work with Henry.

Secretary of State McCord reluctantly agrees to host a holiday party in the hopes of persuading senators in attendance to pass a treaty that requires countries to destroy landmines. Also, Henry tries to find evidence that the Senate Majority Leader exchanged information with the Russians.