Elizabeth, Henry, and Isabelle investigate a plane crash that killed former Secretary of State Vincent Marsh. Nadine reenters the dating scene after she agrees to go on a date with a NASA scientist.

When the State Department goes on lockdown due to a deranged gunman outside the building, Elizabeth is confined with a delegation from Iraq whose translator threatens to reveal damaging information about her actions while in the CIA. Meanwhile, when Matt is stuck in an office with Daisy’s fiancé, Win, he spills information that he shouldn’t have.

When a Texas state trooper is killed by a Mexican cartel smuggler, Elizabeth arranges an extradition deal before going on vacation to celebrate her 25th wedding anniversary in New York City. However, when political issues arise around the case, she is forced to cut their trip short. Also, Elizabeth’s son injures himself while Blake is watching him.

Elizabeth secretly travels to Iran in an attempt to prevent a coup that could impact President Dalton’s administration. Also, she brings her staff up to speed on the investigation into Marsh’s death.