The Stardust Crusaders meet a new addition to their group-a dog named Iggy who is actually the user of The Fool Stand.

Seventeen-year-old Jotaro Kujo refuses to leave his jail cell, believing that he is possessed by an evil spirit. Jotaro's grandfather Joseph Joestar, and the mysterious Mohammed Avdol introduce him to spirit manifestations called Stands.

Jotaro learns the secret of his Stand power and about his family's enemy, the vampire Dio. Later, Jotaro is attacked by Noriaki Kakyoin and his Stand Hierophant Green, an assassin controlled by Dio.