CNO Tom Chandler is sent to Asia to investigate a possible mutation of the Red Flu. Captain Slattery and his crew deliver cure to Southeast Asia but there may be an unexpected threat in the region.

Chandler and crew race to find answers in an Asian Dodge City. Slattery begins to unravel the truth about his troubling predicament.

Chandler must confront his suspected new foe. Slattery learns more about the supposed virus mutation. Pressure mounts on President Michener as the situation worsens.

Chandler's mission becomes complicated as his position is worsened. President Michener faces pressure from the regional leaders.

Chandler's mission comes to a head as he prepares the final part of his plan. President Michener ponders the fate of his presidency.

The Nathan James must evade an overwhelming threat. A revelation in St. Louis puts President Michener in a terrible position.

America copes with tragedy while Chandler further investigates the possible virus mutation.

Chandler finds himself making a difficult decision when an order comes in from the White House.

Chandler faces his powerful enemy in a final showdown. Kara joins someone that can help with her mission.