Alfred and Selina help Bruce search for his parents' killer, Matches Malone; Gordon goes to Edward Nygma with Kristen Kringle's whereabouts; Hugo Strange continues working to reduce the Penguin's aggression.

Gordon races against the clock to save the city from the Alice Tetch Virus, when Lee Thompkins intercepts with a plan of her own. Also, Alfred sees a big change in Bruce Wayne after his work with The Shaman. Meanwhile, some of Gotham's most deranged villains band together.

Gordon and Bullock investigate a location where several kids have been kidnapped. Barbara proves to be an unlikely ally to Gordon. Bruce looks into an alleged witch with healing powers for Selina. Nygma deals with demons of his own.