The bounty on Halstead’s head becomes a serious reality as an innocent bartender takes a bullet meant for him. Olinsky tries to reason with Bembenek to call off the hit. Voight and the team keep this investigation in-house to find the hired assassin. After a tense interaction at district, Platt and Nadia come to an understanding.

Burgess gives chase after Roman is wounded by a hooded perp who opened fire on their patrol car and shoots who she thinks is the suspect, but no gun is found at the scene—and the person she shot is a 17-year-old honor student.

After encouraging her sister to spend a night out with friends, Burgess wakes to find that Nicole never made it home. As the guilt begins to eat at Burgess, the team in Intelligence bands together to make finding Nicole their main priority.

When the team is called to an in-progress bank robbery, they come across Detective Hailey Upton trying to take over the crime scene with her Robbery-Homicide unit - butting heads with Voight in the process. As the robberies continue to be executed around the city, Lindsay is forced to make a decision in the heat of the moment.

In the wake of several gang-related child abductions, Intelligence must race against time to find a kidnapped boy. Owing to their swiftness and military precision, the team scours the VA records and tracks the suspects to a former Army Ranger. With his previous experience as a Ranger, Halstead convinces Voight to send him undercover to try and get information from inside.

When a basketball star is found murdered after an anti-police rally, Intelligence navigates a politically charged environment to track down the killer. To complicate matters further, Woods' daughter Brianna is tangled up in the case.

After discovering the true cause of the high-rise fire, Intelligence races to find the man responsible. And for Halstead, it’s personal.

The crossover starts on Chicago Fire S07E02 Going to War (I) and Chicago Med S04E02 When to Let Go (II).