Dr. James decides to implement a geriatric exercise program in the ward, upsetting Patsy, whose "Make Someone Happy" initiative now includes a live pianist and a fountain. DiDi discloses Patsy's relationship with Dawn to her union rep as proof that her homophobic comment wasn't serious. A homeless woman, and her accompanying stench, is suspiciously dumped in the ward, prompting a staff investigation. Phyllis arrives to check on her dying mother. Dawn wins the grand prize in Dr. James' charity raffle. Dr. James considers relocating after learning she must re-apply for a job she never wanted in the first place.

DiDi deals with her younger sister, who's filling in on the ward and trying to impress Dawn. Dr. James encounters resistance to her research methods, an award goes to Patsy's head, and the staff are anxious to discharge a particular patient.

In the Season 2 finale, disturbing news about the hospice program is revealed by a whistle-blower, which could jeopardize the staff's future. Meanwhile, Dawn finds herself with two suitors; and DiDi discusses her salary issues with Dr. James.

As Dr. Jenna James looks to move past her hospice scandal, she finds her job threatened by a handsome new doctor and takes immediate action. DiDi is inspired to fight for her union rights, while cutbacks force Patsy to return to floor duty. Dawn questions her marriage and, later, gets some distressing news.

While preparing for an upcoming conference, Dr. James is caught off guard by workplace politics. A felon with cancer - and a history of daring escapes - arrives at the ward. When his mother pays a visit, Patsy asks Dawn to pose as someone she's not. DiDi's mother-in-law comes to Billy Barnes for treatment, sparking a family feud.

With the ward's fate up in the air, DiDi hunts for ways to save it, while dealing with pressure from Dawn to be her health advocate. Troublemaking Varla returns, and butts heads with her equally opinionated long-lost daughter. Caught in a mountain of lies, Jenna comes clean to her husband, Richard. After a memorial service full of drama, the staff gets a rude awakening.

In the series finale, DiDi walks a picket line in a last-ditch effort to save the Billy Barnes from closing. Meanwhile, Dr. James regrets an offer made in haste; and a student nurse makes a revelation in a secret-sharing session that gets Patsy's attention.