While Ferdinand helps Malcolm decipher Brother Gregory's writings, Vanessa helps Victor pick a dress for his cousin. Meanwhile, Dorian takes Angelique on a date, and Ethan rescues a young woman from a runaway horse.

After sealing the townhouse against further intrusion, the group goes its separate ways for the moment. Rusk starts asking questions of Ethan, Brona and Victor draw closer, Vanessa teaches Caliban how to dance, and Evelyn launches her next steps in her campaign to seduce Malcolm.

Ethan, now a prisoner under the watchful eye of Scotland Yard Inspector Rusk, is on a train speeding through the desert of the American West. Meanwhile, Sir Malcolm is confronted by a mysterious Native American man in Zanzibar. Back in London, Dr. Frankenstein seeks out his old friend Dr. Jekyll and Vanessa seeks the help of Dr. Seward to battle a new evil.

Lily and Dorian pay a visit to a most unusual show, and Vanessa invites Sweet to a different show. Rusk sets out to track down Ethan and make sure that he hangs, and Henry demonstrates the efficacy of his potion for Victor.

Vanessa asks Seward to hypnotically regress her after learning that she met the Master sometime in the past. Rusk learns that Ethan has a new ally. Caliban finds his wife and child. Lily and Dorian have Justine pledge her service to them.

Ethan, Sir Malcolm and Kaetenay return to London, where Ethan searches for Dr. Frankenstein. Dr. Seward discovers Renfield's secret. Lily reveals a heartbreaking story from Brona Croft's past.