The Turtles face an army of robot foot soldiers; Karai captures Leonardo and forces him to do battle with ninjas that can adapt to his every move.

When the turtles play a Fantasy LARP game to get their minds off things, they separate the difference between fantasy and reality.

When Karai is brainwashed, she begins hunting the Turtles.

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When Mona Lisa suddenly arrives on Earth, Raphael must get her and Bishop to work together to defeat an alien threat and save the Earth

The Newtralizer returns to New York City, more powerful than ever before, and joins forces with a dangerous and unexpected ally. With the help of Raphael's Salamandrian girlfriend, Mona Lisa, the Turtles fight back to defend their city.