While investigating vicious Hellbug attacks, Nolan & Irisa realize they are tied to Irathient spirit raiders that have come into town. Meanwhile, Irisa starts experiencing strange visions.

Interesting relationships develop when the residents of Defiance are forced to stay indoors as a threatening Razor Rain storm approaches. Meanwhile, visions lead Irisa to the Spirit Riders and Sukar, who has fallen under the influence of a strange and mysterious force.

A deadly plague threatens the town; racial tensions rise when the Irathients, who are immune to the virus, are quarantined.