In a wealthy suburb of San Diego, CA, a divorce attorney, Tim MacNeil, and his wife Doreen enjoy a charmed life with their two teenage children. When one family member is brutally murdered, a blood relative's diabolical conspiracy surfaces.

In Tucson, AZ, the churchgoing Sanchez family of six seems perfect. But when the decomposed body of one member is found in the desert, investigators find a killer living very close to home.

In Seminole, FL, police receive two frantic 911 calls from separate members of the Kyne family, each accusing the other of murder.

For the disciplined Kazigo family in Westchester County, NY, secrets bubble to the surface and all roads lead to murder. A hunt for the victim's body leads investigators to unmask one family member hell-bent on revenge.

In suburban Placentia, CA, the Jessee family does battle with cancer, never suspecting another killer lurks within their midst. With survivors pointing fingers at each other, police embark on an epic, decade-long murder investigation.

In the seaside town of Cary, NC, the Britt family lives a charmed existence until the housing market crashes, igniting a blaze of greed that will leave one family member dead and another behind bars.

In Tampa, FL, multimillionaire lottery winner, Jeffrey Dampier, is sharing the wealth with his extended family. But lady luck can be fickle, and this family's red-hot winning streak is soon to end in cold-blooded murder.