In Laceyville, PA, the town barber, Joe Colegrove, and his wife Marlene are thought to be perfect parents with a knack for raising strapping sons. But when half the family is slaughtered in their own beds, all eyes turn to the surviving kin.

In a wealthy suburb of San Diego, CA, a divorce attorney, Tim MacNeil, and his wife Doreen enjoy a charmed life with their two teenage children. When one family member is brutally murdered, a blood relative's diabolical conspiracy surfaces.

In Tucson, AZ, the churchgoing Sanchez family of six seems perfect. But when the decomposed body of one member is found in the desert, investigators find a killer living very close to home.

In Seminole, FL, police receive two frantic 911 calls from separate members of the Kyne family, each accusing the other of murder.

In suburban Placentia, CA, the Jessee family does battle with cancer, never suspecting another killer lurks within their midst. With survivors pointing fingers at each other, police embark on an epic, decade-long murder investigation.

In the seaside town of Cary, NC, the Britt family lives a charmed existence until the housing market crashes, igniting a blaze of greed that will leave one family member dead and another behind bars.