After Dr. Corday moves out, Dr. Green fights loneliness and pain by immersing himself into his work. He is treating a father in the ER who severely burned himself while experimenting with illegal drugs. Abby fumes when the man who beat her is released and moves back in next door; the returning Jerry clashes with fellow desk jockey Frank.

Abby fears the worst when her brother Eric suddenly disappears. Carter and Chen treat a frightened Chinese immigrant nanny, Tong-Yi, whom they suspect was impregnated by her employer. Meanwhile, new surgical resident Paul Nathan, who is struggling to overcome a physical disability, tries to help in the emergency room—but his fellow doctors do not appreciate his advice to patients. Unable to quench his sexual appetites, Kovac also gets into trouble in his professional life, despite his admirable resolve to find an eye specialist to treat a young gunshot victim. Gallant and fellow medical student Erin Harkins engage in an escalating competition of medical knowledge. And Weaver gets some much-needed good news.

The police question Drs. Pratt and Gallant about a rampage at the diner across from the ER. Dr. Lewis befriends her teen admirer, a cancer patient.